Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27403016 | 0.86 | RAB9A (0.40) | L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C | |
| SCHEMBL1646511 | 0.86 | RAB9A (0.40) | L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C | |
| SCHEMBL4741531 | 0.78 | NPSR1 (0.50) | L3MBTL1TDP1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL956511 | 0.78 | CES1 (0.50) | L3MBTL1TDP1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14752641 | 0.77 | HDAC1 (0.60) | L3MBTL1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL10937900 | 0.76 | L3MBTL1 (0.53) | L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C | |
| SCHEMBL6960658 | 0.76 | NPSR1 (0.48) | L3MBTL1TDP1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL1003807 | 0.76 | NPSR1 (0.61) | L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C | |
| SCHEMBL18690253 | 0.76 | CES1 (0.48) | L3MBTL1TDP1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL133668 | 0.74 | KDM4E (0.67) | L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146352-A | Idelalisib intermediate and preparation method thereof | 上海医药工业研究院 | 2016-11-23 | — | — | CN | disclosed |
| CN-106146411-A | (S) preparation method of-2-(1-amino-propyl)-5-fluoro-3-phenyl-3H-quinazoline-4-one | 上海医药工业研究院 | 2016-11-23 | — | — | CN | disclosed |
| US-7589089-B2 | Inhibitors for GlyT-1 | HOFFMANN-LA ROCHE INC. (US) | 2009-09-15 | — | — | US | disclosed |
| US-20080058331-A1 | Inhibitors for GlyT-1 | HOFFMANN-LA ROCHE INC. | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058331-A1 | Inhibitors for GlyT-1 | GLRA1, SLC1A2, AGXT | L3MBTL1 387/4885TDP1 816/4885RAB9A 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.