Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508535 | 0.85 | HSD11B1 (0.70) | ALDH1A1HSD11B1HPGDSMN1; SMN2LMNA | |
| SCHEMBL13675456 | 0.80 | HSD11B1 (0.51) | ALDH1A1HSD11B1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4518867 | 0.79 | HSD11B1 (0.63) | ALDH1A1HSD11B1LMNA | |
| SCHEMBL4511332 | 0.78 | HSD11B1 (0.68) | ALDH1A1HSD11B1TP53SMN1; SMN2KDM4E | |
| SCHEMBL4517638 | 0.77 | HSD11B1 (0.73) | ALDH1A1HSD11B1SMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL4518607 | 0.75 | HSD11B1 (0.63) | ALDH1A1HSD11B1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL4525490 | 0.73 | HSD11B1 (0.63) | ALDH1A1HSD11B1TP53LMNAPOLB | |
| SCHEMBL2986964 | 0.72 | HSD11B1 (1.00) | ALDH1A1HSD11B1TP53SMN1; SMN2KDM4E | |
| SCHEMBL3548392 | 0.71 | HSD11B1 (0.76) | ALDH1A1HSD11B1TP53L3MBTL1 | |
| SCHEMBL3542808 | 0.71 | HSD11B1 (0.84) | ALDH1A1HSD11B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | ALDH1A1 51/4885HSD11B1 1/4885HPGD 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.