Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.58 |
| ▸ | TDP2 | O95551 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838339 | 0.92 | LMNA (0.64) | TSHRLMNAPGRTDP2POLB | |
| SCHEMBL6738366 | 0.91 | TSHR (0.76) | TSHRLMNAPGRPOLBCYP19A1 | |
| SCHEMBL2009026 | 0.89 | TSHR (0.67) | TSHRLMNAPGRPOLBMAPT | |
| SCHEMBL29526232 | 0.89 | TSHR (0.67) | TSHRLMNAPGRPOLBMAPT | |
| SCHEMBL28471286 | 0.89 | TSHR (0.73) | TSHRLMNAPGRPOLBMAPT | |
| Iodide SCHEMBL28598177 | 0.89 | TSHR (0.73) | TSHRLMNAPGRPOLBMAPT | |
| Iodide SCHEMBL30804629 | 0.89 | TSHR (0.73) | TSHRLMNAPGRPOLBMAPT | |
| SCHEMBL11392466 | 0.89 | TSHR (0.73) | TSHRLMNAPGRPOLBMAPT | |
| SCHEMBL11392461 | 0.89 | TSHR (0.73) | TSHRLMNAPGRPOLBMAPT | |
| SCHEMBL30469335 | 0.88 | TSHR (0.64) | TSHRLMNAPGRPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906742-A | Selenophene-fused aromatic compound and manufacturing method thereof | UNIV SEJONG IND ACAD COOP GR | 2014-07-02 | — | — | CN | disclosed |
| US-7570055-B1 | Molecular identification and electron resonance system and method | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2009-08-04 | — | — | US | disclosed |