⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzo[D]Thiazole SCHEMBL900814 | 1.00 | ALDH1A1 (1.00) | — | |
| Benzo[D]Thiazole SCHEMBL8430 | 1.00 | — | — | |
| Benzo[D]Thiazole SCHEMBL10847268 | 1.00 | — | — | |
| Benzo[D]Thiazole SCHEMBL31388426 | 1.00 | — | — | |
| Benzo[D]Thiazole SCHEMBL49903 | 0.97 | ALDH1A1 (0.95) | — | |
| Benzo[D]Thiazole SCHEMBL9551908 | 0.97 | ALDH1A1 (0.95) | — | |
| Benzo[D]Thiazole SCHEMBL7731546 | 0.97 | ALDH1A1 (0.95) | — | |
| Benzo[D]Thiazole SCHEMBL5172231 | 0.97 | ALDH1A1 (0.95) | — | |
| Benzo[D]Thiazole SCHEMBL21679998 | 0.97 | ALDH1A1 (0.95) | — | |
| Benzo[D]Thiazole SCHEMBL8723619 | 0.97 | ALDH1A1 (0.95) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 902 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410120-A | 2-phenylindole amide antitumor compound and application thereof | 四川农业大学 | 2023-07-11 | — | — | CN | claimed |
| CN-110229147-A | A kind of cumarin-benzothiazolyl hydrazone compounds and its preparation method and application | 安徽大学 | 2019-09-13 | — | — | CN | claimed |
| US-20180030033-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-02-01 | — | — | US | claimed |
| US-9790203-B2 | Inhibitor compounds of phosphodiesterase type 10A | ABBVIE INC. (US) | 2017-10-17 | — | — | US | claimed |
| US-9657034-B2 | Substituted furo[3,2-c]pyridines, thieno[3,2-c]pyridines, thieno[2,3-d]pyridazines and pyrido[3,4-d]pyridazines as phosphodiesterase type 10A inhibitors | AbbVie Deuschland GmbH & Co. KG (DE) | 2017-05-23 | — | — | US | claimed |
| US-20160137668-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-05-19 | — | — | US | claimed |
| US-9273068-B2 | Substituted isoquinolines and phthalazines as inhibitors of phosphodiesterase type 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-03-01 | — | — | US | claimed |
| US-20140148461-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-05-29 | — | — | US | claimed |
| US-20130116241-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | ABBVIE INC. (US) | 2013-05-09 | — | — | US | claimed |
| US-20130116233-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | ABBVIE INC. (US) | 2013-05-09 | — | — | US | claimed |
| CN-1330645-C | Benzofuran-2-ones as colorants for organic materials | CIBA SC HOLDING AG (CH) | 2007-08-08 | — | — | CN | claimed |
| EP-1301187-B1 | PURINE-2,6-DIONES WHICH ARE INHIBITORS OF THE ENZYME DIPEPTIDYL PEPTIDASE IV (DPP-IV) | NOVO NORDISK AS (DK) | 2005-07-06 | — | — | EP | claimed |
| US-6872839-B1 | Benzofuran-2-one | CIBASPECIALTY CHEMICALS CORP. (US) | 2005-03-29 | — | — | US | claimed |
| US-6063795-A | ENZYME INHIBITORS | G.D. SEARLE & COMPANY (US) | 2000-05-16 | — | — | US | claimed |
| EP-0751944-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-01-08 | — | — | EP | claimed |
| EP-0023026-B1 | MIXTURES OF OPTICAL BRIGHTENERS AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-22 | — | — | EP | claimed |
| US-4336155-A | CYANOSTYRYL COMPOUNDS AND OTHER BRIGHTENER | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-22 | — | — | US | claimed |
| US-4330427-A | Mixtures of optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-18 | — | — | US | claimed |
| WO-2024151809-A1 | INHIBITORS OF BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE 2 (BMPR2) AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2024-07-18 | — | — | WO | disclosed |
| US-4330427-A | Mixtures of optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-18 | — | — | US | disclosed |