Diphenylsulfane

Diphenylsulfane

SCHEMBL451795

[NaH].c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.56
MAPT P10636 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MGLL Q99685 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MAOA P21397 3/20 0.55
MAOB P27338 3/20 0.55
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 3/20 0.47
HTR2C P28335 1/20 0.44
HTR6 P50406 1/20 0.44
SLC6A4 P31645 1/20 0.44
NR1H2 P55055 1/20 0.42
DDAH1 O94760 1/20 0.42
NOS1 P29475 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
CHRNA7 P36544 1/20 0.41
HTT P42858 1/20 0.41
TUBB4A P04350 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL451796 1.00 HPGD (0.56) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL27611905 0.96 HPGD (0.60) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL27714827 0.96 HPGD (0.60) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL7109540 0.96 HPGD (0.60) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL28332331 0.96 HPGD (0.60) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL452 0.96 HPGD (0.60) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL23277364 0.92 MAOA (0.62) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL3891151 0.92 MAOA (0.62) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL6554424 0.92 HPGD (0.56) HPGDMAPTSMN1; SMN2MGLLHSD17B10
Diphenylsulfane SCHEMBL5417674 0.92 HPGD (0.56) HPGDMAPTSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4584146-A Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites THE B. F. GOODRICH COMPANY (US) 1986-04-22 US claimed
US-11254650-B1 Use of pnictogenium compounds in carbon-carbon bond formation SOUTHEASTERN LOUISIANA UNIVERSITY (US) 2022-02-22 US disclosed
CN-109312056-B Epoxy compound, curable composition containing same, and cured product obtained by curing curable composition JXTG能源株式会社 2021-10-01 CN disclosed
CN-109311906-B Epoxy compound, curable composition containing same, and cured product obtained by curing curable composition JXTG能源株式会社 2021-08-03 CN disclosed
CN-113072684-A Curable composition and cured product obtained by curing same JXTG能源株式会社 2021-07-06 CN disclosed
CN-109071776-B Curable composition and cured product obtained by curing same JXTG能源株式会社 2021-06-08 CN disclosed
EP-1888727-B1 NEW DHA DERIVATIVES AND THEIR USE AS MEDICAMENTS PRONOVA BIOPHARMA NORGE AS (NO) 2015-04-15 EP disclosed
CN-103058867-B Novel DHA derivatives for and uses thereof as medicament PRONOVA BIOCARE AS 2015-03-25 CN disclosed
US-8618165-B2 Compounds PRONOVA BIOPHARMA NORGE AS (NO) 2013-12-31 US disclosed
CN-103058867-A Fatty acid analogues, i.e. dha derivatives for uses as a medicament PRONOVA BIOCARE AS 2013-04-24 CN disclosed
EP-0004773-B1 17-BETA-THIOCARBOXYLIC ACID ESTERS OF 4-HALO-3-OXOANDROST-4-ENES, THEIR PHARMACEUTICAL USE AND PROCESSES FOR THEIR PREPARATION SYNTEX (U.S.A.) INC. (US) 1981-04-29 EP disclosed
US-4264499-A PSYCHOTROPIC AGENTS, ANXIOLYTICS, ANTICONVULSANTS, HYOTICS SHIONOGI & CO., LTD. (JP) 1981-04-28 US disclosed
EP-0004741-B1 THIO ETIANIC ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL USE SYNTEX (U.S.A.) INC. (US) 1981-01-28 EP disclosed
US-4231930-A PSYCHOTROPIC AGENTS, ANXIOLYTICS, ANTICONVULSANTS, HYPNOTICS SHIONOGI & CO., LTD. (JP) 1980-11-04 US disclosed
US-4198403-A ANTIINFLAMMATORY AGENTS SYNTEX (U.S.A.) INC. (US) 1980-04-15 US disclosed
US-4188385-A ANTIINFLAMMATORY STERIODS SYNTEX (U.S.A.) INC. (US) 1980-02-12 US disclosed
US-4187301-A ANTIINFLAMMATORY AGENTS SYNTEX (U.S.A.) INC. (US) 1980-02-05 US disclosed
EP-0004773-A2 17-Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes, their pharmaceutical use and processes for their preparation SYNTEX (U.S.A.) INC. (US) 1979-10-17 EP disclosed
EP-0004741-A2 Thio etianic acid derivatives, their preparation and pharmaceutical use SYNTEX (U.S.A.) INC. (US) 1979-10-17 EP disclosed
EP-0004320-A1 1-Substituted-thiomethyltriazolobenzodiazepines, preparation thereof, their use, and a pharmaceutical composition SHIONOGI & CO., LTD. (JP) 1979-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11254650-B1 Use of pnictogenium compounds in carbon-carbon bond formation MASTL, PHYKPL, HRH3 HPGD 2672/4885MAPT 4685/4885SMN1; SMN2 4740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.