Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282806 | 0.86 | PKM (0.66) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL12934291 | 0.82 | PKM (0.70) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL27299229 | 0.81 | PKM (0.68) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL22775064 | 0.80 | PKM (0.62) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL3827561 | 0.78 | PKM (0.55) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL12064248 | 0.78 | PKM (0.75) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL7295778 | 0.77 | PKM (0.35) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL24599226 | 0.77 | PKM (0.81) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL12934303 | 0.77 | PKM (0.62) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL8540155 | 0.75 | PKM (0.84) | PKMKDM4ETHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626022-B2 | Racemic mixtures; oxidation; cyclization; crystallization | CHIRACON GMBH (DE) | 2009-12-01 | — | — | US | disclosed |
| US-20050080263-A1 | Method for producing ss-heteroaryl-alpha-alanine compounds using 2-amino-2-(heteroarylmethyl) carboxylic acid compounds | CHIRACON GMBH (DE) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080263-A1 | Method for producing ss-heteroaryl-alpha-alanine compounds using 2-amino-2-(heteroarylmethyl) carboxylic acid compounds | AAAS, ASNS, AADAT | PKM 1628/4885KDM4E 4443/4885THRB 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.