Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.82 |
| ▸ | ACACA | Q13085 | 2/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520477 | 0.93 | ACACB (0.77) | ACACBACACAKCNH2 | |
| Trifluoroacetic Acid SCHEMBL4261177 | 0.87 | ACACB (0.65) | ACACBACACAKCNH2 | |
| SCHEMBL4509544 | 0.86 | ACACB (1.00) | ACACB | |
| SCHEMBL4507766 | 0.83 | ACACB (0.60) | ACACBACACAKCNH2 | |
| SCHEMBL4504145 | 0.83 | ACACB (0.83) | ACACB | |
| SCHEMBL4519791 | 0.81 | ACACB (0.62) | ACACBACACA | |
| SCHEMBL4268374 | 0.81 | ACACB (0.60) | ACACBACACA | |
| Trifluoroacetic Acid SCHEMBL4264817 | 0.81 | ACACB (0.88) | ACACBACACA | |
| SCHEMBL4509550 | 0.81 | ACACB (1.00) | ACACBACACA | |
| SCHEMBL12903889 | 0.80 | ACACB (1.00) | ACACBACACAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | CORBETT JEFFREY WAYNE | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | ACACA, PC, ACACB | ACACB 3/4885ACACA 1/4885KCNH2 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.