SCHEMBL4520907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21457956	0.85	ATM (0.57)	ATMCTSSCTSKCTSLCTSB
	SCHEMBL28356132	0.83	ATM (0.52)	ATMCTSSCTSKCTSLCTSB
	SCHEMBL4332764	0.83	NPC1 (0.50)	ATMMEN1LMNAKMT2ANPSR1
	SCHEMBL18930493	0.82	CTSS (0.50)	ATMCTSSCTSKCTSLCTSB
	SCHEMBL12203694	0.82	NPC1 (0.63)	ATMCTSSCTSKCTSLCTSB
	SCHEMBL9299789	0.82	ATM (0.63)	ATMCTSSCTSKCTSLCTSB
	SCHEMBL3676162	0.82	NPC1 (0.63)	ATMCTSSCTSKCTSLCTSB
	SCHEMBL29401299	0.82	NPC1 (0.63)	ATMCTSSCTSKCTSLCTSB
	SCHEMBL7939304	0.82	ATM (0.63)	ATMCTSSCTSKCTSLCTSB
	SCHEMBL3676166	0.82	NPC1 (0.63)	ATMCTSSCTSKCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.