SCHEMBL145170

SCHEMBL145170

Oc1ccc(CC(O)CCc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.62
DPP4 P27487 1/20 0.59
OPRK1 P41145 2/20 0.53
KDM4E B2RXH2 1/20 0.51
SIGMAR1 Q99720 1/20 0.50
TRPA1 O75762 1/20 0.49
ANPEP P15144 2/20 0.48
ERAP2 Q6P179 2/20 0.48
ERAP1 Q9NZ08 2/20 0.48
LAP3 P28838 1/20 0.48
ENPEP Q07075 1/20 0.48
ADRA1A P35348 2/20 0.48
GRIN2D O15399 1/20 0.48
GRIN3B O60391 1/20 0.48
ADRA1D P25100 1/20 0.48
ADRA1B P35368 1/20 0.48
GRIN1 Q05586 1/20 0.48
GRIN2A Q12879 1/20 0.48
GRIN2B Q13224 1/20 0.48
GRIN2C Q14957 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452092 0.92 ESR1 (0.54) TRPV1DPP4KDM4EADRB2ADRB1
SCHEMBL448011 0.90 TRPA1 (0.56) TRPV1DPP4TRPA1ANPEPERAP2
SCHEMBL25272355 0.84 TRPV1 (0.58) TRPV1DPP4OPRK1KDM4ESIGMAR1
SCHEMBL9224378 0.83 OPRK1 (0.54) TRPV1DPP4OPRK1KDM4ESIGMAR1
SCHEMBL28156577 0.82 TRPV1 (0.65) TRPV1DPP4OPRK1KDM4ESIGMAR1
SCHEMBL28156578 0.82 TRPV1 (0.65) TRPV1DPP4OPRK1KDM4ESIGMAR1
SCHEMBL7270279 0.82 ESR1 (0.62) TRPV1DPP4OPRK1KDM4ESIGMAR1
SCHEMBL5807651 0.80 OPRK1 (0.59) DPP4OPRK1KDM4EADRA1AADRA1D
SCHEMBL3215341 0.80 OPRK1 (0.59) TRPV1OPRK1KDM4ESIGMAR1ADRA1A
SCHEMBL6675718 0.80 ANPEP (0.57) TRPV1DPP4OPRK1KDM4ESIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
EP-2195440-A2 BIOFUEL PRODUCTION Bio Architecture Lab, Inc. (US) 2010-06-16 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
US-20230295678-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2023-09-21 US disclosed
EP-4098750-A1 RAPID PRETREATMENT Sweetwater Energy, Inc. (US) 2022-12-07 EP disclosed
EP-3230463-B1 RAPID PRETREATMENT SWEETWATER ENERGY INC (US) 2022-05-25 EP disclosed
US-11332723-B2 Engineered microorganisms for production of commodity chemicals and cellular biomass THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-17 US disclosed
CN-107208120-B Rapid pretreatment 斯威特沃特能源公司 2021-11-23 CN disclosed
US-20210040524-A1 RAPID PRETREATMENT APALTA TEHNOLOOGIA OÜ (EE) 2021-02-11 US disclosed
US-20090203089-A1 ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF BIO ARCHITECTURE LAB, INC. (US) 2009-08-13 US disclosed
WO-2009097346-A2 ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF BIO ARCHITECTURE LAB, INC. (US) 2009-08-06 WO disclosed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US disclosed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US disclosed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO disclosed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO disclosed
US-5453443-A Antiallergens, antiinflammatory MERCK FROSST CANADA, INC. (CA) 1995-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA TRPV1 3969/4885DPP4 961/4885OPRK1 4494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.