Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.50 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 4/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521007 | 1.00 | USP1 (0.50) | USP1WDR48PDE5AACP1MEN1 | |
| SCHEMBL4521016 | 1.00 | USP1 (0.50) | USP1WDR48PDE5AACP1MEN1 | |
| SCHEMBL4497588 | 0.92 | PDE10A (0.49) | USP1WDR48PDE5AACP1MEN1 | |
| SCHEMBL4497594 | 0.92 | PDE10A (0.49) | USP1WDR48PDE5AACP1MEN1 | |
| SCHEMBL4497598 | 0.92 | PDE10A (0.49) | USP1WDR48PDE5AACP1MEN1 | |
| SCHEMBL8229988 | 0.92 | ACP1 (0.49) | USP1WDR48PDE5AACP1MEN1 | |
| SCHEMBL4514622 | 0.92 | ACP1 (0.51) | PDE5AACP1MEN1KMT2AMAPT | |
| SCHEMBL4514611 | 0.92 | ACP1 (0.51) | PDE5AACP1MEN1KMT2AMAPT | |
| SCHEMBL8227557 | 0.92 | ACP1 (0.51) | PDE5AACP1MEN1KMT2AMAPT | |
| SCHEMBL4514616 | 0.92 | ACP1 (0.51) | PDE5AACP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | PKD2, PKD1, AADAT | USP1 4530/4885WDR48 2739/4885PDE5A 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.