Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499412 | 0.90 | F10 (0.49) | F10 | |
| SCHEMBL4524147 | 0.89 | F10 (0.52) | F10 | |
| SCHEMBL4503804 | 0.82 | F10 (0.47) | F10ALDH1A1 | |
| SCHEMBL8298336 | 0.82 | F10 (0.48) | F10 | |
| SCHEMBL13958556 | 0.79 | F10 (0.52) | F10ALDH1A1 | |
| SCHEMBL4505509 | 0.74 | F10 (0.57) | F10 | |
| SCHEMBL8299588 | 0.72 | F10 (0.55) | F10 | |
| SCHEMBL13958546 | 0.72 | F10 (0.59) | F10 | |
| SCHEMBL4508161 | 0.72 | F10 (0.35) | F10 | |
| SCHEMBL5691287 | 0.71 | F10 (0.60) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482374-B2 | Pyrrolidine-2-ones as Factor Xa inhibitors | GLAXO GROUP LIMITED (GB) | 2009-01-27 | — | — | US | disclosed |
| US-20060167079-A1 | Pyrrolidine -2-ones as factor xa inhibitors | GLAXO GROUP LIMITED (GB) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167079-A1 | Pyrrolidine -2-ones as factor xa inhibitors | TFPI, F2, F11 | F10 10/4885ALDH1A1 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.