SCHEMBL4521730

SCHEMBL4521730

CC(C)CC(C)(C)CC(CCCC(=O)O)(CC(C)(C)CC(C)C)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.33
LMNA P02545 2/20 0.33
SLC22A6 Q4U2R8 2/20 0.33
FFAR1 O14842 2/20 0.33
NAALAD2 Q9Y3Q0 1/20 0.33
CPT2 P23786 1/20 0.33
AKR1B1 P15121 1/20 0.32
TSHR P16473 5/20 0.32
NFKB1 P19838 1/20 0.32
PMP22 Q01453 1/20 0.32
GPR84 Q9NQS5 7/20 0.31
PPARG P37231 6/20 0.31
PPARD Q03181 6/20 0.31
PPARA Q07869 6/20 0.31
HDAC11 Q96DB2 5/20 0.31
ALDH1A1 P00352 2/20 0.31
TLR2 O60603 2/20 0.31
FABP4 P15090 2/20 0.31
PTPN1 P18031 2/20 0.31
SLC22A8 Q8TCC7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4526151 0.93 TDP1 (0.39) TDP1LMNASLC22A6FFAR1CPT2
SCHEMBL536369 0.85 LMNA (0.39) TDP1LMNASLC22A6FFAR1AKR1B1
SCHEMBL2230547 0.80 LMNA (0.42) TDP1LMNASLC22A6FFAR1AKR1B1
SCHEMBL27998682 0.79 TSHR (0.44) TDP1LMNASLC22A6FFAR1TSHR
SCHEMBL4534219 0.79 TSHR (0.44) TDP1LMNASLC22A6FFAR1TSHR
SCHEMBL8682820 0.79 TSHR (0.44) TDP1LMNASLC22A6FFAR1TSHR
SCHEMBL21114063 0.79 TSHR (0.44) TDP1LMNASLC22A6FFAR1TSHR
SCHEMBL6652661 0.78 KDM4C (0.42) TDP1LMNASLC22A6FFAR1AKR1B1
SCHEMBL1110756 0.77 AMPD2 (0.36) TDP1LMNASLC22A6FFAR1NAALAD2
SCHEMBL18343639 0.77 AMPD2 (0.36) LMNASLC22A6AKR1B1TSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130040867-A1 TRUNK PISTON ENGINE LUBRICATING OIL COMPOSITIONS CHEVRON ORONITE TECHNOLOGY B.V. (US) 2013-02-14 US disclosed
US-8318643-B2 Trunk piston engine lubricating oil compositions Cherron Oronite Technology B.V. (NL) 2012-11-27 US disclosed
US-8207098-B2 Lubricant additive, lubricant composition and grease composition YAMANASHI UNIVERSITY (JP) 2012-06-26 US disclosed
US-20110319304-A1 Trunk piston engine lubricating oil compositions CHEVRON ORONITE TECHNOLOGY B.V. (NL) 2011-12-29 US disclosed
US-20090239773-A1 LUBRICANT ADDITIVE, LUBRICANT COMPOSITION AND GREASE COMPOSITION YAMANASHI UNIVERSITY (JP) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239773-A1 LUBRICANT ADDITIVE, LUBRICANT COMPOSITION AND GREASE COMPOSITION GRN, GRIA1, GRIK5 TDP1 334/4885LMNA 3546/4885SLC22A6 2953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.