SCHEMBL4521745

SCHEMBL4521745

CC=C(C)[SiH2]CCCCCCCCCCCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.38
THRB P10828 3/20 0.38
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
LMNA P02545 4/20 0.36
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
MAPT P10636 3/20 0.32
GMNN O75496 2/20 0.32
GLA P06280 2/20 0.32
POLB P06746 2/20 0.32
CETP P11597 2/20 0.32
MAPK1 P28482 2/20 0.32
CXCR5 P32302 2/20 0.32
CCR6 P51684 2/20 0.32
BLM P54132 2/20 0.32
UBE2N P61088 2/20 0.32
SPHK2 Q9NRA0 2/20 0.32
SPHK1 Q9NYA1 2/20 0.32
CYP2D6 P10635 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8381900 0.98 TSHR (0.33) TSHRTHRBMEN1KMT2ALMNA
SCHEMBL6534691 0.81 LMNA (0.36) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL20536748 0.77
SCHEMBL20536323 0.76
SCHEMBL20537041 0.74
SCHEMBL20537062 0.74
SCHEMBL20536945 0.74
SCHEMBL20536706 0.74
SCHEMBL20537066 0.74
SCHEMBL4533307 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197903-B2 Surface modified organic inorganic hybrid glass, protecting group induced alcohol or its derivative and producing method thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2012-06-12 US disclosed
US-20090274910-A1 Surface Modified Organic Inorganic Hybrid Glass, Protecting Group Induced Alcohol or Its Derivative and Producing Method Thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2009-11-05 US disclosed
WO-2007120014-A1 SURFACE MODIFIED ORGANIC·INORGANIC HYBRID GLASS, PROTECTING GROUP INDUCED ALCOHOL OR ITS DERIVATIVE AND PRODUCING METHOD THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2007-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274910-A1 Surface Modified Organic Inorganic Hybrid Glass, Protecting Group Induced Alcohol or Its Derivative and Producing Method Thereof VIM, ICAM1, ILK TSHR 3919/4885THRB 3965/4885MEN1 3169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.