Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4523137 | 0.79 | CYP1A2 (0.52) | GRNSORT1CYP1A2CYP2C9HIF1A | |
| SCHEMBL16892796 | 0.78 | ACE (0.58) | FAAHACE | |
| SCHEMBL3658568 | 0.74 | HRH4 (0.53) | PIN1ACEALDH1A1 | |
| SCHEMBL14265381 | 0.74 | PTPN1 (0.54) | GRNSORT1CYP1A2CYP2C9HIF1A | |
| SCHEMBL4534450 | 0.74 | PTPN1 (0.54) | GRNSORT1CYP1A2CYP2C9HIF1A | |
| SCHEMBL20467686 | 0.73 | GPR132 (0.48) | CYP1A2CYP2C9FAAHACE | |
| SCHEMBL21837579 | 0.73 | GPR132 (0.48) | CYP1A2CYP2C9FAAHACE | |
| SCHEMBL9233015 | 0.71 | MEN1 (0.48) | GRNSORT1CYP1A2CYP2C9HIF1A | |
| SCHEMBL21837370 | 0.70 | ACE (0.49) | CYP1A2CYP2C9PIN1FAAHACE | |
| SCHEMBL21837371 | 0.70 | ACE (0.49) | CYP1A2CYP2C9PIN1FAAHACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080263-A1 | Method for producing ss-heteroaryl-alpha-alanine compounds using 2-amino-2-(heteroarylmethyl) carboxylic acid compounds | CHIRACON GMBH (DE) | 2005-04-14 | — | — | US | claimed |
| US-7626022-B2 | Racemic mixtures; oxidation; cyclization; crystallization | CHIRACON GMBH (DE) | 2009-12-01 | — | — | US | disclosed |
| US-20050080263-A1 | Method for producing ss-heteroaryl-alpha-alanine compounds using 2-amino-2-(heteroarylmethyl) carboxylic acid compounds | CHIRACON GMBH (DE) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080263-A1 | Method for producing ss-heteroaryl-alpha-alanine compounds using 2-amino-2-(heteroarylmethyl) carboxylic acid compounds | AAAS, ASNS, AADAT | GRN 3433/4885SORT1 2599/4885CYP1A2 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.