SCHEMBL4522061

SCHEMBL4522061

OCCOCCOCCOCCCCCCCCCCCSSCCCCCCCCCCCOCCOCCOCCO

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
THRB P10828 1/20 0.58
HTT P42858 1/20 0.58
MAPT P10636 1/20 0.58
TSHR P16473 2/20 0.48
MAPK1 P28482 2/20 0.48
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.34
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
CASP1 P29466 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLCO1B3 Q9NPD5 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13736760 1.00 MEN1 (0.58) MEN1KMT2ATHRBHTTMAPT
SCHEMBL10026225 1.00 MEN1 (0.58) MEN1KMT2ATHRBHTTMAPT
SCHEMBL823818 0.98 MEN1 (0.54) MEN1KMT2ATHRBHTTMAPT
SCHEMBL13668048 0.90 MEN1 (0.58) MEN1KMT2ATHRBHTTMAPT
SCHEMBL10026227 0.90 MEN1 (0.77) MEN1KMT2ATHRBHTTMAPT
SCHEMBL2288544 0.87 TSHR (0.56) MEN1KMT2ATHRBHTTMAPT
SCHEMBL16609231 0.84 MEN1 (0.75) MEN1KMT2ATHRBHTTMAPT
SCHEMBL5191031 0.84 MEN1 (0.75) MEN1KMT2ATHRBHTTMAPT
SCHEMBL4433304 0.84 MEN1 (0.75) MEN1KMT2ATHRBHTTMAPT
SCHEMBL12754637 0.84 MEN1 (0.75) MEN1KMT2ATHRBHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090325262-A1 Immobilization of biological molecules onto surfaces coated with monolayers SURFACE LOGIX, INC. 2009-12-31 US disclosed
US-7439056-B2 Peelable and resealable devices for arraying materials SURFACE LOGIX INC. (US) 2008-10-21 US disclosed
US-7371563-B2 Peelable and resealable devices for biochemical assays SURFACE LOGIX, INC. (US) 2008-05-13 US disclosed
US-7351575-B2 Methods for processing biological materials using peelable and resealable devices SURFACE LOGIX, INC. (US) 2008-04-01 US disclosed
US-7001740-B2 Methods of arraying biological materials using peelable and resealable devices SURFACE LOGIX, INC. (US) 2006-02-21 US disclosed
US-6967074-B2 Methods of detecting immobilized biomolecules SURFACE LOGIX, INC. (US) 2005-11-22 US disclosed
US-20050250097-A1 METHODS OF ARRAYING BIOLOGICAL MATERIALS USING PEELABLE AND RESEALABLE DEVICES SURFACE LOGIX, LLC 2005-11-10 US disclosed
US-20050100974-A1 METHODS OF DETECTING IMMOBILIZED BIOMOLECULES SURFACE LOGIX, LLC 2005-05-12 US disclosed
US-6803205-B2 MONITORING ENZYME ACTIVITY IN SAMPLE; OBTAIN ENZYME SAMPLE, INSERT INTO RESEALABLE APPARATUS, EXPOSE TO SUBSTRATE, MEASURE ENZYME ACTIVITY SURFACE LOGIX, INC. 2004-10-12 US disclosed
US-20030073228-A1 Peelable and resealable devices for arraying materials SURFACE LOGIX, LLC 2003-04-17 US disclosed
US-20030032046-A1 Peelable and resealable devices for biochemical assays SURFACE LOGIX, LLC 2003-02-13 US disclosed
US-20030032076-A1 Methods of measuring enzyme activity using peelable and resealable devices SURFACE LOGIX, LLC 2003-02-13 US disclosed
WO-2003012392-A2 RESEALABLE AND SEALABLE DEVICES FOR BIOCHEMICAL ASSAYS SURFACE LOGIX, INC. (US) 2003-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090325262-A1 Immobilization of biological molecules onto surfaces coated with monolayers EPCAM, ICAM1, MB MEN1 3145/4885KMT2A 1870/4885THRB 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.