Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13668048 | 0.97 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL823818 | 0.90 | MEN1 (0.54) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL24589046 | 0.89 | TSHR (0.60) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL22455497 | 0.89 | TSHR (0.74) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL13736760 | 0.87 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL4522061 | 0.87 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL10026225 | 0.87 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL26353320 | 0.87 | MEN1 (0.46) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL22703312 | 0.83 | TSHR (0.43) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL8674724 | 0.82 | TSHR (0.62) | TSHRMAPK1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113122032-B | Primer composition and laminate | 财团法人工业技术研究院 | 2022-03-15 | — | — | CN | claimed |
| EP-4008722-A1 | NOVEL RIG-I LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-3398956-B1 | NOVEL RIG-I LIGANDS AND METHODS FOR PRODUCING THEM | UNIV BONN RHEINISCHE FRIEDRICH WILHELMS (DE) | 2021-11-03 | — | — | EP | disclosed |
| US-11142763-B2 | RIG-I ligands and methods for producing them | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2021-10-12 | — | — | US | disclosed |
| EP-3199538-B1 | PURIFICATION OF TRIPHOSPHORYLATED OLIGONUCLEOTIDES USING CAPTURE TAGS AND MODIFIED TRIPHOSPHORYLATED OLIGONUCLEOTIDES AS ACTIVATORS OF RIG-1 HELICASE | UNIV BONN RHEINISCHE FRIEDRICH WILHELMS (DE) | 2020-05-27 | — | — | EP | disclosed |
| EP-3398956-A1 | NOVEL RIG-I LIGANDS AND METHODS FOR PRODUCING THEM | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2018-11-07 | — | — | EP | disclosed |
| US-20180312841-A1 | NOVEL RIG-I LIGANDS AND METHODS FOR PRODUCING THEM | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2018-11-01 | — | — | US | disclosed |
| US-10072262-B2 | RIG-I ligands and methods for producing them | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2018-09-11 | — | — | US | disclosed |
| US-10059943-B2 | RIG-I ligands and methods for producing them | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2018-08-28 | — | — | US | disclosed |
| EP-2903997-B1 | NOVEL RIG-I LIGANDS AND METHODS FOR PRODUCING THEM | UNIV BONN RHEINISCHE FRIEDRICH WILHELMS (DE) | 2018-06-06 | — | — | EP | disclosed |
| US-20150275217-A1 | NOVEL RIG-I LIGANDS AND METHODS FOR PRODUCING THEM | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2015-10-01 | — | — | US | disclosed |
| EP-2903997-A1 | NOVEL RIG-I LIGANDS AND METHODS FOR PRODUCING THEM | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2015-08-12 | — | — | EP | disclosed |
| US-8679859-B2 | Method for functionalizing materials and devices comprising such materials | State of Oregon by and through the State Board of Higher Education on behalf of Porland State University (US) | 2014-03-25 | — | — | US | disclosed |
| US-20140024819-A1 | PURIFICATION OF TRIPHOSPHORYLATED OLIGONUCLEOTIDES USING CAPTURE TAGS | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAET BONN (DE) | 2014-01-23 | — | — | US | disclosed |
| EP-2508530-A1 | Purification of triphosphorylated oligonucleotides using capture tags | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011097092-A2 | SOLID-SUPPORTED ETHER DISULFIDES | BERRY AND ASSOCIATES, INC. (US) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011097092-A2 | SOLID-SUPPORTED ETHER DISULFIDES | BERRY AND ASSOCIATES, INC. (US) | 2011-08-11 | — | — | WO | disclosed |
| US-20110190485-A1 | SOLID-SUPPORTED ETHER DISULFIDES | BERRY AND ASSOCIATES, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110190485-A1 | SOLID-SUPPORTED ETHER DISULFIDES | BERRY AND ASSOCIATES, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| US-20100028559-A1 | Method for functionalizing materials and devices comprising such materials | THE STATE OF OREGON ACTING BY AND THROUGH STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190485-A1 | SOLID-SUPPORTED ETHER DISULFIDES | NSUN3, NSUN2, SNRPA1 | TSHR 463/4885MAPK1 3154/4885MEN1 2694/4885 |
| US-20100028559-A1 | Method for functionalizing materials and devices comprising such materials | ALDH1A2, LGALS3, LGALS3BP | TSHR 3335/4885MAPK1 3113/4885MEN1 3122/4885 |
| US-20150275217-A1 | NOVEL RIG-I LIGANDS AND METHODS FOR PRODUCING THEM | MAVS, EIF2AK2, DDX5 | TSHR 2469/4885MAPK1 4517/4885MEN1 4853/4885 |
| US-11142763-B2 | RIG-I ligands and methods for producing them | MAVS, EIF2AK2, ADAR | TSHR 1949/4885MAPK1 4641/4885MEN1 4867/4885 |
| US-10072262-B2 | RIG-I ligands and methods for producing them | MAVS, EIF2AK2, ADAR | TSHR 1949/4885MAPK1 4641/4885MEN1 4867/4885 |
| US-20140024819-A1 | PURIFICATION OF TRIPHOSPHORYLATED OLIGONUCLEOTIDES USING CAPTURE TAGS | TYMP, NUDT1, ITPA | TSHR 779/4885MAPK1 4511/4885MEN1 3536/4885 |
| US-20180312841-A1 | NOVEL RIG-I LIGANDS AND METHODS FOR PRODUCING THEM | MAVS, EIF2AK2, DDX5 | TSHR 2469/4885MAPK1 4517/4885MEN1 4853/4885 |
| US-10059943-B2 | RIG-I ligands and methods for producing them | MAVS, EIF2AK2, ADAR | TSHR 1949/4885MAPK1 4641/4885MEN1 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.