SCHEMBL452262

SCHEMBL452262

[c]1ccc2[c]ccnc2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451881 0.83
SCHEMBL8727 0.73 ALDH1A1 (0.41)
SCHEMBL25470 0.72 KDM4E (0.32)
SCHEMBL16317 0.70 KDM4A (0.32)
SCHEMBL3130393 0.68
SCHEMBL5461210 0.68
SCHEMBL217998 0.68 NR4A2 (0.47)
SCHEMBL450508 0.68 MAPT (0.38)
SCHEMBL857946 0.67 CDK5 (0.37)
SCHEMBL4471481 0.67 ALDH1A1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5367038-A Polyisoquinolinediyls and uses thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 1994-11-22 US claimed
CN-113166098-A Triazine compound, material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-07-23 CN disclosed
EP-2626346-B1 BENZO[K]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT CONTAINING SAME IDEMITSU KOSAN CO (JP) 2018-01-10 EP disclosed
CN-102574797-B Benzo [ k ] fluoranthene derivative and organic electroluminescent element containing same 出光兴产株式会社 2017-03-01 CN disclosed
US-9273002-B2 Benzo[k]fluoranthene derivative and organic electroluminescence device containing the same IDEMITSU KOSAN CO., LTD. (JP) 2016-03-01 US disclosed
US-20150216861-A1 CYCLOPROPYL AMIDE DERIVATIVES ASTRAZENECA AB (SE) 2015-08-06 US disclosed
US-9029381-B2 Cyclopropyl amide derivatives ASTRAZENECA AB (SE) 2015-05-12 US disclosed
EP-2805937-A1 Cyclopropyl amide derivatives AstraZeneca AB (SE) 2014-11-26 EP disclosed
EP-2253615-B1 Cyclopropyl amide derivatives ASTRAZENECA AB (SE) 2014-07-09 EP disclosed
EP-2195293-B1 CYCLOPTOPYL AMIDE DERIVATIVES ASTRAZENECA AB (SE) 2013-10-16 EP disclosed
US-20090076020-A1 Cyclopropyl Amide Derivatives 978 ASTRAZENECA AB (SE) 2009-03-19 US disclosed
WO-2009024823-A2 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS ASTRAZENECA AB (SE) 2009-02-26 WO disclosed
EP-0773248-B1 Polymers with heterocyclic side groups MISSISSIPPI POLYMER TECHNOLOGI (US) 2002-10-02 EP disclosed
US-6166210-A Perylene imide monocarboxylic acids CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-12-26 US disclosed
EP-1053228-A1 PERYLENE IMIDE MONOCARBOXYLIC ACIDS AS COLORANTS Ciba SC Holding AG (CH) 2000-11-22 EP disclosed
WO-1999031069-A1 PERYLENE IMIDE MONOCARBOXYLIC ACIDS AS COLORANTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-06-24 WO disclosed
US-5668245-A PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS MAXDEM INCORPORATED (US) 1997-09-16 US disclosed
EP-0773248-A1 Polymers with heterocyclic side groups MAXDEM INCORPORATED (US) 1997-05-14 EP disclosed
US-5367038-A Polyisoquinolinediyls and uses thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 1994-11-22 US disclosed
US-5244992-A Poly(iso)quinolinediyls and preparation and use thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 1993-09-14 US disclosed