Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 12/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 11/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 11/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206281 | 0.87 | ALDH1A1 (0.41) | CDK2CCNA2CCNA1NTRK1PAK4 | |
| SCHEMBL6532636 | 0.82 | CDK2 (0.43) | CDK2CCNA2CCNA1NTRK1PAK4 | |
| SCHEMBL12892427 | 0.81 | CDK2 (0.40) | CDK2CCNA2CCNA1NTRK1PAK4 | |
| SCHEMBL4521702 | 0.81 | CCNA2 (0.41) | CDK2CCNA2CCNA1NTRK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17956348 | 0.80 | CCNA2 (0.41) | CDK2CCNA2CCNA1NTRK1ALDH1A1 | |
| SCHEMBL4516226 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL1205765 | 0.79 | ALDH1A1 (0.41) | CDK2CCNA2CCNA1NTRK1PAK4 | |
| SCHEMBL1204698 | 0.78 | CCNA2 (0.39) | CDK2CCNA2CCNA1KCNQ3KCNQ2 | |
| SCHEMBL1205098 | 0.75 | CDK2 (0.42) | CDK2CCNA2CCNA1NTRK1PAK4 | |
| SCHEMBL1205756 | 0.74 | MEN1 (0.42) | CDK2NPC1ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979356-B1 | CARBONYLAMINO PYRROLOPYRAZOLES, POTENT KINASE INHIBITORS | PFIZER PROD INC (US) | 2013-09-18 | — | — | EP | disclosed |
| US-20090318440-A1 | CARBONYLAMINO PYRROLOPYRAZOLES, POTENT KINASE INHIBITORS | PFIZER INC. | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318440-A1 | CARBONYLAMINO PYRROLOPYRAZOLES, POTENT KINASE INHIBITORS | PAK4, PAK5, PAK3 | CDK2 128/4885CCNA2 1698/4885CCNA1 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.