Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.74 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.74 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.74 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.74 |
| ▸ | MMP13 | P45452 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518602 | 0.87 | HDAC1 (0.76) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL5089680 | 0.86 | HDAC1 (0.73) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL31235656 | 0.85 | HDAC1 (0.76) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL9212451 | 0.85 | HDAC1 (0.76) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL7742536 | 0.83 | HDAC1 (0.70) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL31746240 | 0.82 | HDAC1 (0.61) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL7734745 | 0.81 | HDAC1 (0.90) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL2242298 | 0.80 | SMN1; SMN2 (0.74) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL5803935 | 0.80 | HDAC1 (0.68) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL416296 | 0.80 | HDAC1 (0.64) | HDAC1HDAC3HDAC2HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409621-B | Targeted dopamine D 3 Diagnosis and treatment medicine for receptor and application thereof | 江苏省原子医学研究所 | 2023-09-08 | — | — | CN | claimed |
| CN-114409621-A | Targeted dopamine D3Receptor diagnosis and treatment medicine and application thereof | 江苏省原子医学研究所 | 2022-04-29 | — | — | CN | claimed |
| CN-114409621-B | Targeted dopamine D 3 Diagnosis and treatment medicine for receptor and application thereof | 江苏省原子医学研究所 | 2023-09-08 | — | — | CN | disclosed |
| CN-114409621-A | Targeted dopamine D3Receptor diagnosis and treatment medicine and application thereof | 江苏省原子医学研究所 | 2022-04-29 | — | — | CN | disclosed |
| US-20090238761-A1 | Novel Aryl Piperazine Derivatives With Medical Utility | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238761-A1 | Novel Aryl Piperazine Derivatives With Medical Utility | HTR2C, HTR2A, DRD2 | HDAC1 2598/4885HDAC3 868/4885HDAC2 684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.