Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28231228 | 0.78 | SLC1A2 (0.40) | SLC1A2ALDH1A1KMT2AATMPKM | |
| SCHEMBL4522866 | 0.78 | SLC1A2 (0.40) | SLC1A2ALDH1A1KMT2AATMPKM | |
| SCHEMBL21917309 | 0.78 | SLC1A2 (0.39) | SLC1A2ALDH1A1KMT2AATMPKM | |
| SCHEMBL5590839 | 0.77 | SLC1A2 (0.45) | SLC1A2ALDH1A1KMT2AATMMEN1 | |
| Ethylene Glycol SCHEMBL3521351 | 0.76 | SLC1A2 (0.47) | SLC1A2ALDH1A1KMT2AATMPKM | |
| SCHEMBL30327623 | 0.76 | SLC1A2 (0.41) | SLC1A2ALDH1A1KMT2AATMPKM | |
| SCHEMBL28918361 | 0.75 | MAPT (0.38) | ALDH1A1KMT2AATMPKM | |
| SCHEMBL3507385 | 0.75 | KMT2A (0.40) | SLC1A2ALDH1A1KMT2AATMPKM | |
| SCHEMBL9351173 | 0.73 | TSHR (0.34) | ALDH1A1KMT2APKMTSHR | |
| SCHEMBL26177011 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3393496-A1 | LONG-ACTING GLP-1R AGONIST AS A THERAPY OF NEUROLOGICAL AND NEURODEGENERATIVE CONDITIONS | The Johns Hopkins University (US) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017112889-A1 | LONG-ACTING GLP-1R AGONIST AS A THERAPY OF NEUROLOGICAL AND NEURODEGENERATIVE CONDITIONS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-06-29 | — | — | WO | disclosed |