Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.71 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL10878598 | 1.00 | FFAR3 (0.71) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL219329 | 1.00 | FFAR3 (0.71) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL5711851 | 1.00 | — | — | |
| Propionic Acid SCHEMBL10877398 | 1.00 | FFAR3 (0.71) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL2463993 | 0.97 | FFAR3 (0.67) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL28965995 | 0.97 | FFAR3 (0.67) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL242079 | 0.97 | FFAR3 (0.67) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL29198011 | 0.97 | FFAR3 (0.67) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL8646907 | 0.94 | FFAR3 (0.62) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL29012488 | 0.94 | FFAR3 (0.62) | FFAR3GLRA1SLC6A9OR51E2GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724808-B | Olefin epoxidation method | 中国石油化工股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| US-11898250-B2 | Formulation for the etching of polymer materials prior to coating of the materials | AVANZARE INNOVACIÓN TECNOLÓGICA, S.L. (ES) | 2024-02-13 | — | — | US | claimed |
| CN-117417793-A | Cleaning agent for deep hole machining and preparation method thereof | 常州工程职业技术学院 | 2024-01-19 | — | — | CN | claimed |
| CN-116059428-B | Antibacterial night absorbent core with red buttocks prevention function and super-large absorption capacity and application thereof | 露乐健康科技股份有限公司 | 2023-10-20 | — | — | CN | claimed |
| EP-3719105-B1 | CLEANING FORMULATION FOR REMOVING RESIDUES ON SURFACES | FUJIFILM ELECTRONIC MAT USA INC (US) | 2023-09-27 | — | — | EP | claimed |
| CN-114258424-B | Etching composition | 富士胶片电子材料美国有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-116059428-A | Antibacterial night absorbent core with red buttocks prevention function and super-large absorption capacity and application thereof | 露乐健康科技股份有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-115960684-A | Vehicle hard surface compositions containing graphene | 伊利诺斯工具制品有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-115044375-A | Etching composition | 富士胶片电子材料美国有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-111201091-B | Formulations for etching polymeric materials prior to coating thereof | 阿万扎雷创新科技有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-102976441-A | Method for improving backwashing drainage water quality of oilfield produced water filter | CHINA NAT PETROLEUM CORP | 2013-03-20 | — | — | CN | claimed |
| CN-102066445-B | Method for producing phenol novolac resin and resin-coated sand using phenol novolac resin | HITACHI CHEMICAL CO LTD | 2012-12-26 | — | — | CN | claimed |
| CN-102066445-A | Method for producing phenol novolac resin and resin-coated sand using phenol novolac resin | HITACHI CHEMICAL CO LTD | 2011-05-18 | — | — | CN | claimed |
| CN-1834087-A | organic iodine complex | ZENG XIONGFEI (CN) | 2006-09-20 | — | — | CN | claimed |
| US-20040245214-A1 | Electroless plating apparatus and post-electroless plating cleaning method | EBARA CORPORATION (JP) | 2004-12-09 | — | — | US | claimed |
| WO-2004006305-A1 | ELECTROLESS PLATING APPARATUS AND POST-ELECTROLESS PLATING CLEANING METHOD | EBARA CORPORATION (JP) | 2004-01-15 | — | — | WO | claimed |
| EP-0945496-B1 | Ink compositions and multicolor thermal ink jet printing process for the production of high quality images | XEROX CORP (US) | 2003-11-12 | — | — | EP | claimed |
| EP-0945496-A1 | Ink compositions and multicolor thermal ink jet printing process for the production of high quality images | Xerox Corporation (US) | 1999-09-29 | — | — | EP | claimed |
| US-5958121-A | SET OF INKS COMPRISING FIRST AQUEOUS INK CONSISTING OF ANIONIC COLORANT, SECOND AQUEOUS INK CONTAINING AMMONIUM SALT, WHEREIN FIRST COLORANT IS IMMOBILIZED ON SUBSTRATE BY INTERACTION WITH AMMONIUM SALT, REDUCING INTERCOLOR BLEED | XEROX CORPORATION (US) | 1999-09-28 | — | — | US | claimed |
| CN-1115712-A | Hydrogen peroxide solution brightener for wheat straw and bamboo products | REN DAHUA (CN) | 1996-01-31 | — | — | CN | claimed |