Acetophenone

Acetophenone

SCHEMBL4522953

CC(=O)c1ccccc1.O=C(O)c1cc(O)c2ccccc2c1O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.77
MCL1 Q07820 9/20 0.70
MAPT P10636 3/20 0.70
KDM4E B2RXH2 2/20 0.70
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
POLB P06746 2/20 0.70
NSD2 O96028 1/20 0.70
HSD17B10 Q99714 3/20 0.57
CYP2C9 P11712 2/20 0.57
HPGD P15428 2/20 0.57
TSHR P16473 1/20 0.57
ALOX12 P18054 1/20 0.57
ATIC P31939 1/20 0.57
HTT P42858 2/20 0.54
ALDH1A1 P00352 1/20 0.54
PKM P14618 1/20 0.54
HMGB1 P09429 1/20 0.53
CXCL12 P48061 1/20 0.53
LDHA P00338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317180 0.88 THRB (1.00) THRBMCL1MAPTKDM4EMEN1
Methylamine SCHEMBL9769432 0.86 THRB (0.89) THRBMCL1MAPTKDM4EMEN1
SCHEMBL10902143 0.83 MAPT (1.00) THRBMCL1MAPTKDM4EMEN1
SCHEMBL29904678 0.83 MAPT (1.00) THRBMCL1MAPTKDM4EMEN1
SCHEMBL2788817 0.81 HSD17B10 (0.54) THRBMCL1MAPTKDM4EMEN1
SCHEMBL9303548 0.80 THRB (0.70) THRBMCL1MAPTKDM4EMEN1
Niacin SCHEMBL27576966 0.78 THRB (0.67) THRBMCL1MAPTKDM4EMEN1
SCHEMBL5539615 0.75 HSD17B10 (0.88) THRBMCL1MAPTKDM4EMEN1
SCHEMBL9618861 0.75 HSD17B10 (0.74) THRBMCL1MAPTKDM4EMEN1
Triphenylene SCHEMBL10947667 0.74 MAPT (0.62) MAPTMEN1KMT2APOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009215619-A SILVER FINE PARTICLE EXCELLENT IN AFFINITY WITH KETONE, AND SILVER INK DOWA ELECTRONICS MATERIALS CO LTD 2009-09-24 JP disclosed