Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | NSD2 | O96028 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742045 | 0.85 | THRB (0.55) | THRBMEN1KMT2AMCL1KDM4E | |
| SCHEMBL317180 | 0.82 | THRB (1.00) | THRBMEN1KMT2AMCL1KDM4E | |
| SCHEMBL245255 | 0.81 | BCL2 (0.62) | MEN1KMT2AMCL1KDM4EMAPT | |
| SCHEMBL7046942 | 0.80 | KMT2A (0.70) | MEN1KMT2AMCL1KDM4EMAPT | |
| SCHEMBL7437398 | 0.80 | GAA (0.64) | MEN1KMT2AMCL1KDM4EMAPT | |
| Acetophenone SCHEMBL4522953 | 0.80 | THRB (0.77) | THRBMEN1KMT2AMCL1KDM4E | |
| SCHEMBL29106579 | 0.79 | BCL2 (0.60) | MEN1KMT2AMCL1KDM4EMAPT | |
| Benzophenone SCHEMBL28941308 | 0.79 | BCL2 (0.60) | MEN1KMT2AMCL1KDM4EMAPT | |
| SCHEMBL6695828 | 0.79 | THRB (0.71) | THRBMEN1KMT2AMCL1KDM4E | |
| SCHEMBL15313729 | 0.78 | BCL2 (0.68) | MEN1KMT2AMCL1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318993-A | Antihyperlipidemic benzoquinones | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-07 | — | — | US | disclosed |