Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2080112 | 0.88 | KDM4E (0.67) | NEK2KDM4EMALT1RECQLKMT2A | |
| SCHEMBL14335272 | 0.85 | MALT1 (0.61) | NEK2KDM4EMALT1RECQLKMT2A | |
| SCHEMBL2421306 | 0.84 | MALT1 (0.70) | NEK2KDM4ECYP2C19MALT1KMT2A | |
| SCHEMBL14334510 | 0.83 | MALT1 (0.60) | NEK2KDM4EMALT1RECQLKMT2A | |
| SCHEMBL14334180 | 0.83 | MALT1 (0.52) | NEK2KDM4EMALT1RECQLKMT2A | |
| SCHEMBL4533155 | 0.83 | MALT1 (0.54) | NEK2KDM4EMALT1RECQLKMT2A | |
| SCHEMBL3104049 | 0.83 | NEK2 (0.59) | NEK2KDM4ECYP2C19MALT1RECQL | |
| SCHEMBL238160 | 0.82 | KDM4E (0.60) | NEK2KDM4ECYP2C19MALT1RECQL | |
| SCHEMBL4879872 | 0.82 | KDM4E (0.60) | NEK2KDM4ECYP2C19MALT1RECQL | |
| SCHEMBL4697505 | 0.82 | MALT1 (0.48) | NEK2KDM4EMALT1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501440-B2 | Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-03-10 | — | — | US | disclosed |
| US-20040266768-A1 | Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266768-A1 | Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use | SLC5A2, HPD, DPP4 | NEK2 2324/4885KDM4E 1444/4885CYP2C19 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.