Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883842 | 1.00 | TSHR (0.41) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL4533485 | 0.98 | TSHR (0.37) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL9784627 | 0.81 | TSHR (0.44) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL1931465 | 0.81 | TSHR (0.44) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL9205173 | 0.81 | TSHR (0.44) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL3335340 | 0.81 | TSHR (0.44) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL9216022 | 0.81 | TSHR (0.44) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL7389147 | 0.81 | TSHR (0.44) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL6242253 | 0.81 | TSHR (0.44) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL223057 | 0.81 | TSHR (0.44) | TSHRFAAHTRPV1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601772-B2 | Nano-composite and method thereof | BRIDGESTONE CORPORATION | 2009-10-13 | — | — | US | disclosed |
| US-20070161734-A1 | Comprising clay and cationic mediator such as imidazolium compound wherein cationic mediator comprises hydrophobic unit and cationic unit; use in preparing products such as tires with improved and well-balanced properties including gas impermeability, cure rates, and superior mechanical characteristics | BRIDGESTONE CORPORATION (JP) | 2007-07-12 | — | — | US | disclosed |