Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TEAD4 | Q15561 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.44 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078827 | 0.83 | KDM4E (0.53) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL3558568 | 0.81 | KDM4E (0.65) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL1158367 | 0.79 | KDM4E (0.50) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL622814 | 0.79 | KDM4E (0.50) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL18120558 | 0.79 | KDM4E (0.66) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11332652 | 0.79 | KDM4E (0.50) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL3555239 | 0.79 | KDM4E (0.54) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6786876 | 0.79 | KDM4E (0.50) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13395932 | 0.76 | KDM4E (0.51) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL21173510 | 0.76 | KDM4E (0.59) | KDM4EPOLBALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152765-A1 | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 2004-08-05 | — | — | US | claimed |
| US-20020082293-A1 | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 2002-06-27 | — | — | US | claimed |
| EP-0422466-A1 | Endermic preparation of external application | Sansho Seiyaku Co., Ltd. (JP) | 1991-04-17 | — | — | EP | claimed |
| US-7557094-B2 | Skin cream composition | ETHICS COSMECEUTICALS AB (SE) | 2009-07-07 | — | — | US | disclosed |
| US-7425340-B2 | Permeation enhancing compositions for anticholinergic agents | ANTARES PHARMA IPL AG (CH) | 2008-09-16 | — | — | US | disclosed |
| EP-1742664-A1 | PERMEATION ENHANCING COMPOSITIONS FOR ANTICHOLINERGIC AGENTS | Antares Pharma IPL AG (CH) | 2007-01-17 | — | — | EP | disclosed |
| EP-1341517-B1 | A SKIN CREAM COMPOSITION | ETHICS COSMECEUTICALS AB (SE) | 2006-09-06 | — | — | EP | disclosed |
| US-20050287194-A1 | Permeation enhancing compositions for anticholinergic agents | ANTARES PHARMA, INC. | 2005-12-29 | — | — | US | disclosed |
| WO-2005107812-A1 | PERMEATION ENHANCING COMPOSITIONS FOR ANTICHOLINERGIC AGENTS | ANTARES PHARMA IPL AG (CH) | 2005-11-17 | — | — | WO | disclosed |
| US-20040152765-A1 | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 2004-08-05 | — | — | US | disclosed |
| US-20040152765-A1 | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 2004-08-05 | — | — | US | disclosed |
| US-20040043963-A1 | Skin cream composition | WADLUND AS (NO) | 2004-03-04 | — | — | US | disclosed |
| US-20020082293-A1 | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 2002-06-27 | — | — | US | disclosed |
| US-20020082293-A1 | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 2002-06-27 | — | — | US | disclosed |
| US-6300369-B1 | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 2001-10-09 | — | — | US | disclosed |
| US-6300369-B1 | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 2001-10-09 | — | — | US | disclosed |
| US-5874463-A | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 1999-02-23 | — | — | US | disclosed |
| US-5874463-A | Hydroxy-kojic acid skin peel | PHYSICIAN'S CHOICE OF ARIZONA, INC. | 1999-02-23 | — | — | US | disclosed |
| EP-0422466-A1 | Endermic preparation of external application | Sansho Seiyaku Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |
| EP-0422466-A1 | Endermic preparation of external application | Sansho Seiyaku Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050287194-A1 | Permeation enhancing compositions for anticholinergic agents | SLC18A3, SLC14A1, UTS2R | KDM4E 4306/4885POLB 610/4885ALDH1A1 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.