⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4525850 | 0.85 | MGLL (0.33) | — | |
| SCHEMBL6079452 | 0.84 | MEN1 (0.41) | — | |
| SCHEMBL4520059 | 0.79 | CYP2D6 (0.45) | — | |
| SCHEMBL4528810 | 0.73 | — | — | |
| SCHEMBL4535041 | 0.72 | — | — | |
| SCHEMBL6079536 | 0.70 | CYP2D6 (0.42) | — | |
| SCHEMBL6078372 | 0.69 | F10 (0.43) | — | |
| SCHEMBL6078862 | 0.65 | — | — | |
| SCHEMBL4530692 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL4537767 | 0.64 | SIGMAR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076015-A1 | Tricyclic Spiro Compound Comprising Acyl Group Bound to Nitrogen Atom in the Ring | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
| EP-1864984-A1 | TRICYCLIC SPIRO COMPOUND COMPRISING ACYL GROUP BOUND TO NITROGEN ATOM IN THE RING | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2007-12-12 | — | — | EP | disclosed |