Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | BLM | P54132 | 2/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TYMS | P04818 | 1/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.56 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL767202 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4516719 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4517389 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL767221 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4530130 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4532973 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4524881 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL768276 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL767253 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4539444 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123516-A1 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-05-14 | — | — | US | disclosed |
| WO-2007019478-A2 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-02-15 | — | — | WO | disclosed |