Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | BLM | P54132 | 2/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TYMS | P04818 | 1/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.56 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL767202 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4516719 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4517389 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL767221 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4530130 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4532973 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4524881 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL767253 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4526841 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL4539444 | 1.00 | LMNA (0.79) | LMNABLMCYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118879388-A | Special cutting fluid for stainless steel and preparation method thereof | 沧州鑫润特种润滑剂有限公司 | 2024-11-01 | — | — | CN | disclosed |
| US-9511392-B2 | Method for coating metal surfaces in a multi-step method | CHEMETALL GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| EP-2648675-A1 | HAIR RELAXING AND STRAIGHTENING COMPOSITIONS | International Flora Technologies, Ltd. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078658-A1 | HAIR RELAXING AND STRAIGHTENING COMPOSITIONS | INTERNATIONAL FLORA TECHNOLOGIES, LTD. (US) | 2012-06-14 | — | — | WO | disclosed |
| US-20120148517-A1 | Hair Relaxing and Straightening Compositions | INTERNATIONAL FLORA TECHNOLOGIES, LTD. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120070674-A1 | METHOD FOR COATING METAL SURFACES IN A MULTI-STEP METHOD | CHEMETALL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20090123516-A1 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-05-14 | — | — | US | disclosed |
| WO-2003014244-A1 | BINDING AGENT COMPONENT FOR SURFACE COATING AGENTS WITH IMPROVED ADHESIVE PROPERTIES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-02-20 | — | — | WO | disclosed |
| US-5277788-A | Twice-anodized aluminum article having an organo-phosphorus monolayer and process for making the article | ALUMINUM COMPANY OF AMERICA (US) | 1994-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148517-A1 | Hair Relaxing and Straightening Compositions | PDE6G, SHH, DNMT3L | LMNA 272/4885BLM 337/4885CYP3A4 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.