SCHEMBL452778

SCHEMBL452778

C=C1COCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL9487554 0.92 LMNA (0.39)
SCHEMBL2572530 0.69
SCHEMBL7908874 0.67
SCHEMBL9915833 0.67
SCHEMBL268473 0.67
SCHEMBL5533502 0.63
SCHEMBL278292 0.62 LMNA (0.42)
SCHEMBL4394616 0.62
SCHEMBL11821405 0.62
SCHEMBL9257592 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3573981-B1 ALKOXY BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION UCB Biopharma SRL (BE) 2022-03-16 EP claimed
US-11091474-B2 Alkoxy bis-heteroaryl derivatives as modulators of protein aggregation UCB Biopharma SRL (BE) 2021-08-17 US claimed
US-20200291013-A1 ALKOXY BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION UCB BIOPHARMA SPRL (BE) 2020-09-17 US claimed
CN-110191885-A ALKOXY BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION UCB生物制药私人有限公司 2019-08-30 CN claimed
WO-2018138085-A1 ALKOXY BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION UCB BIOPHARMA SPRL (BE) 2018-08-02 WO claimed
EP-0597853-B1 AUTOMATIC LIGHT VALVES CHAHROUDI DAY (US) 2002-03-20 EP claimed
US-5404245-A Automatic light valves with polymeric layer containing network of bonds CHAHROUDI DAY (US) 1995-04-04 US claimed
US-5377042-A Two cover layers with inner layer of homogenous solutions of polymer and solvent that separate to give more reflection of light CHAHROUDI DAY (US) 1994-12-27 US claimed
US-4251399-A AN ELASTOMER, AND AN ORGANIC PEROXIDE DAIKIN KOGYO CO., LTD. (JP) 1981-02-17 US claimed
EP-4217398-B1 ANTI-C-MET ANTIBODY DRUG CONJUGATES ABBVIE MFG MANAGEMENT UNLIMITED COMPANY (IE) 2025-09-24 EP disclosed
US-11970512-B2 Amphotericin B derivatives with improved therapeutic index THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-04-30 US disclosed
CN-110407898-B Amphotericin B derivatives with improved therapeutic index 伊利诺伊大学评议会 2023-12-01 CN disclosed
EP-3827004-B1 4-(1,3,4-OXADIAZOLE-2-YL)PYRIDINE-2(1H)-ONE DERIVATIVES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS FOR THE TREATMENT OF E.G. INFECTIONS CHONG KUN DANG PHARMACEUTICAL CORP (KR) 2023-10-11 EP disclosed
CN-110191885-B Alkoxy bis-heteroaryl derivatives as modulators of protein aggregation UCB生物制药私人有限公司 2023-05-16 CN disclosed
EP-0597853-A4 AUTOMATIC LIGHT VALVES. CHAHROUDI DAY (US) 1994-11-30 EP disclosed
EP-0597853-A1 AUTOMATIC LIGHT VALVES CHAHROUDI, Day (US) 1994-05-25 EP disclosed
EP-0581649-A1 New method of production of 20-keto 21(S)-hydroxy steroids and intermediates thereof ROUSSEL UCLAF (FR) 1994-02-02 EP disclosed
WO-1993002380-A1 AUTOMATIC LIGHT VALVES CHAHROUDI DAY (US) 1993-02-04 WO disclosed
US-4260698-A Co-crosslinkable blend composition comprising iodine-containing fluoroelastomer DAIKIN KOGYO CO., LTD. (JP) 1981-04-07 US disclosed
US-4251399-A AN ELASTOMER, AND AN ORGANIC PEROXIDE DAIKIN KOGYO CO., LTD. (JP) 1981-02-17 US disclosed