SCHEMBL278292

SCHEMBL278292

O=C1COCCO1.O=C1COCCO1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
GAA P10253 1/20 0.40
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
CRHBP P24387 2/20 0.32
CRHR2 Q13324 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HTT P42858 1/20 0.32
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4394616 1.00
SCHEMBL1933520 1.00 LMNA (0.42) LMNAALDH1A1TP53TSHRGAA
SCHEMBL29008 1.00
SCHEMBL7200305 0.97 GAA (0.44) LMNAALDH1A1TP53TSHRGAA
SCHEMBL6121060 0.97 GAA (0.44) LMNAALDH1A1TP53TSHRGAA
Methane SCHEMBL29072799 0.97
SCHEMBL10985053 0.97
Dioxane SCHEMBL6669275 0.97 GAA (0.44) LMNAALDH1A1TP53TSHRGAA
SCHEMBL1933467 0.97 GAA (0.44) LMNAALDH1A1TP53TSHRGAA
SCHEMBL11522424 0.91 LMNA (0.40) LMNAALDH1A1TP53TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10501761-B2 Processing biomass to obtain hydroxylcarboxylic acids XYLECO, INC. (US) 2019-12-10 US claimed
US-20160076062-A1 PROCESSING BIOMASS TO OBTAIN HYDROXYLCARBOXYLIC ACIDS XYLECO, INC. 2016-03-17 US claimed
US-20160053047-A1 PROCESSING BIOMASS XYLECO, INC. 2016-02-25 US claimed
EP-2413981-A1 THICK FOAMS FOR BIOMEDICAL APPLICATIONS AND METHODS OF MAKING Advanced Technologies and Regenerative Medicine, LLC (US) 2012-02-08 EP claimed
US-20110034388-A1 COLLAGEN AND FIBRIN MICROTHREADS IN A DISCRETE THREAD MODEL OF IN VITRO ACL SCAFFOLD REGENERATION WORCESTER POLYTECHNIC INSTITUTE 2011-02-10 US claimed
EP-1491156-B1 Porous resorbable graft fixation pin DEPUY MITEK INC (US) 2008-12-31 EP claimed
WO-2001002033-A1 PROCESS FOR MANUFACTURING BIOMEDICAL FOAMS ETHICON, INC. (US) 2001-01-11 WO claimed
US-11612491-B2 Zero profile spinal fusion cage DePuy Synthes Products, Inc. (US) 2023-03-28 US disclosed
US-20230020338-A1 ZERO PROFILE SPINAL FUSION CAGE DEPUY SYNTHES PRODUCTS INC (US) 2023-01-19 US disclosed
US-20200208180-A1 PROCESSING BIOMASS TO OBTAIN HYDROXYLCARBOXYLIC ACIDS XYLECO, INC. (US) 2020-07-02 US disclosed
US-10624758-B2 Zero profile spinal fusion cage DePuy Synthes Products, Inc. (US) 2020-04-21 US disclosed
US-10501761-B2 Processing biomass to obtain hydroxylcarboxylic acids XYLECO, INC. (US) 2019-12-10 US disclosed
US-20190322800-A1 PROCESSING HYDROXY-CARBOXYLIC ACIDS TO POLYMERS XYLECO, INC. (US) 2019-10-24 US disclosed
US-20080311087-A1 Human Umbilical Tissue-Derived Cell Compositions for the Treatment of Incontinence ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE, LLC 2008-12-18 US disclosed
US-20080102123-A1 Self-gelling tunable drug delivery system ENDO-SURGERY, INC. 2008-05-01 US disclosed
US-20070270854-A1 Bone anchoring device LI ZHIGANG 2007-11-22 US disclosed
US-20070213750-A1 Composite Staple for Completing an Anastomosis ETHICON, INC. (US) 2007-09-13 US disclosed
US-20060153815-A1 Tissue engineering devices for the repair and regeneration of tissue ETHICON, INC. 2006-07-13 US disclosed
US-20060058834-A1 Foam matrix embolization device CORDIS CORPORATION 2006-03-16 US disclosed
WO-2001002033-A1 PROCESS FOR MANUFACTURING BIOMEDICAL FOAMS ETHICON, INC. (US) 2001-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160053047-A1 PROCESSING BIOMASS SCD, FASN, PFAS LMNA 1329/4885ALDH1A1 1704/4885TP53 1992/4885
US-20060153815-A1 Tissue engineering devices for the repair and regeneration of tissue ILK, PGF, KRT18 LMNA 1974/4885ALDH1A1 3045/4885TP53 1771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.