Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.50 |
| ▸ | FDPS | P14324 | 11/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL4528458 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL5828967 | 0.97 | LPAR3 (0.54) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL27523489 | 0.97 | LPAR3 (0.54) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL27610207 | 0.97 | LPAR3 (0.54) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Hexanethiol SCHEMBL5828935 | 0.97 | LPAR3 (0.54) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL5829436 | 0.92 | GABBR2 (0.46) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| SCHEMBL3371221 | 0.90 | LPAR3 (0.46) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| SCHEMBL3875770 | 0.90 | LPAR3 (0.46) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Hexane SCHEMBL18769800 | 0.85 | LPAR3 (0.63) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Hexane SCHEMBL6862689 | 0.85 | LPAR3 (0.63) | LPAR3LPAR2FDPSGGPS1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7599134-B2 | Vision system | GENTEX CORPORATION (US) | 2009-10-06 | — | — | US | disclosed |
| US-20090040629-A1 | Vision System | BECHTEL JON H | 2009-02-12 | — | — | US | disclosed |
| EP-2005233-A2 | IMPROVED VISION SYSTEM | Gentex Corporation (US) | 2008-12-24 | — | — | EP | disclosed |
| US-7423821-B2 | Vision system | GENTEX CORPORATION (US) | 2008-09-09 | — | — | US | disclosed |
| WO-2007111984-A2 | IMPROVED VISION SYSTEM | GENTEX CORPORATION (US) | 2007-10-04 | — | — | WO | disclosed |
| US-20070221826-A1 | Vision system | GENTEX CORPORATION | 2007-09-27 | — | — | US | disclosed |