SCHEMBL452864

SCHEMBL452864

CCOC(=O)C(CC)C(=O)OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
TDP1 Q9NUW8 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 3/20 0.37
TSHR P16473 2/20 0.37
HSD17B10 Q99714 1/20 0.37
GAA P10253 2/20 0.36
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
MMP8 P22894 1/20 0.34
HPGD P15428 1/20 0.34
RECQL P46063 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TRPA1 O75762 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063173 0.91 TSHR (0.43) ALDH1A1LMNATSHRHSD17B10GAA
SCHEMBL230068 0.86 ALDH1A1 (0.50) ALDH1A1TDP1MEN1KMT2ALMNA
SCHEMBL15549609 0.85 MAPT (0.38) ALDH1A1TDP1MEN1KMT2ALMNA
Benzene SCHEMBL28181561 0.84 TSHR (0.42) MEN1KMT2ALMNATSHRGAA
SCHEMBL28054134 0.84 ALDH1A1 (0.48) ALDH1A1TDP1MEN1KMT2ALMNA
SCHEMBL28077349 0.84 ALDH1A1 (0.48) ALDH1A1TDP1MEN1KMT2ALMNA
SCHEMBL26658212 0.84 ALDH1A1 (0.48) ALDH1A1TDP1MEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL27522636 0.84 ALDH1A1 (0.48) ALDH1A1TDP1MEN1KMT2ALMNA
Ammonia Solution, Strong SCHEMBL27830684 0.84 ALDH1A1 (0.48) ALDH1A1TDP1MEN1KMT2ALMNA
SCHEMBL27450452 0.83 ALOX15 (0.38) ALDH1A1TDP1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115449900-B Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer 浙江奥首材料科技有限公司 2023-11-21 CN claimed
CN-115449900-A Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer 浙江奥首材料科技有限公司 2022-12-09 CN claimed
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN claimed
CN-104513332-B Catalyst system and its application for olefinic polymerization 中国石油化工股份有限公司 2017-06-06 CN claimed
CN-104513327-B Olefin polymerization catalyst composition and applications thereof 中国石油化工股份有限公司 2017-02-15 CN claimed
CN-105315390-A Catalyst composition for olefin polymerization and application thereof BEIJING COMBINE TECH CO LTD 2016-02-10 CN claimed
CN-104513332-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513330-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513327-A Olefin polymerization catalyst composition and applications thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
US-20240191594-A1 Cement Top Jobs In Wellbore Annuli Using Expandable Compositions CHEVRON U.S.A. INC. 2024-06-13 US disclosed
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2024-01-30 US disclosed
US-20240026206-A1 METHODS OF USING EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON AUSTRALIA PTY LTD (AU) 2024-01-25 US disclosed
US-20240026749-A1 DEPLOYMENT METHODS FOR EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON AUSTRALIA PTY LTD (AU) 2024-01-25 US disclosed
CN-115449900-B Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer 浙江奥首材料科技有限公司 2023-11-21 CN disclosed
EP-0916701-A1 CRYSTALLINE POLYPROPYLENE RESIN COMPOSITION Grand Polymer Co., Ltd. (JP) 1999-05-19 EP disclosed
US-5482939-A ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-01-09 US disclosed
US-5389633-A ANTIASTHMATIC AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-14 US disclosed
EP-0562439-A1 Triazolopyridazines as antioasthmatics TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-29 EP disclosed
EP-0361365-A1 Aminobenzoic and aminocyclohexane-carboylic acid compounds, compositions, and their method of use E.R. SQUIBB & SONS, INC. (US) 1990-04-04 EP disclosed
EP-0321218-A2 Process for producing polypropylene and stretched polypropylene film MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions PTGER4, PTGER1, PTGER3 ALDH1A1 654/4885TDP1 3033/4885MEN1 3177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.