Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31682144 | 0.91 | LMNA (0.46) | ALDH1A1HMGCRLMNACYP2D6SPHK1 | |
| SCHEMBL31682134 | 0.91 | LMNA (0.46) | ALDH1A1HMGCRLMNACYP2D6SPHK1 | |
| SCHEMBL31682128 | 0.91 | LMNA (0.46) | ALDH1A1HMGCRLMNACYP2D6SPHK1 | |
| SCHEMBL736817 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HMGCRLMNADNM1SPHK1 | |
| SCHEMBL12003762 | 0.81 | HMGCR (0.45) | ALDH1A1HMGCRDNM1FDPS | |
| SCHEMBL16673449 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNACYP2D6DNM1SPHK1 | |
| SCHEMBL2535364 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HMGCRLMNADNM1SPHK1 | |
| SCHEMBL4534677 | 0.77 | — | — | |
| SCHEMBL6361700 | 0.77 | HMGCR (0.46) | ALDH1A1HMGCRLMNASMN1; SMN2 | |
| SCHEMBL6137606 | 0.77 | HMGCR (0.46) | ALDH1A1HMGCRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619125-B2 | Hydrogenation promoter, hydrogenation catalyst, and process for producing alkene compound | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2009-11-17 | — | — | US | disclosed |
| US-20080033221-A1 | Hydrogenation Promoter, Hydrogenation Catalyst, and Process for Producing Alkene Compound | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2008-02-07 | — | — | US | disclosed |