SCHEMBL4528959

SCHEMBL4528959

CCO[Si](OCC)(OCC)c1ccc(C(F)(F)F)cc1.CO[Si](OC)(OC)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.33
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
MAPK1 P28482 1/20 0.32
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
IDO1 P14902 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15736462 0.86 HPGD (0.39) HPGDMAPK1NR1H2NR1H3TSHR
SCHEMBL15738099 0.86 HPGD (0.39) HPGDMAPK1NR1H2NR1H3TSHR
SCHEMBL446489 0.84 HPGD (0.41) HPGDMAPK1NR1H2NR1H3TSHR
SCHEMBL15736073 0.81 KIF11 (0.44) HPGD
SCHEMBL15737478 0.81 KIF11 (0.44) HPGD
SCHEMBL15735163 0.79 KIF11 (0.48) HPGDNR1H2NR1H3
SCHEMBL15737384 0.77
SCHEMBL15737430 0.77
SCHEMBL4898228 0.75 KIF11 (0.43) TSHRSMN1; SMN2IDO1NPSR1
SCHEMBL8639721 0.73 NQO1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090166818-A1 Positive Photosensitive Resin Composition, and Semiconductor Device and Display Therewith SUMITOMO BAKELITE COMPANY LIMITED (JP) 2009-07-02 US disclosed
EP-1965256-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, AND SEMICONDUCTOR DEVICE AND DISPLAY USING SAME SUMITOMO BAKELITE CO., LTD. (JP) 2008-09-03 EP disclosed