Lithium Ion

Lithium Ion

SCHEMBL452900

CC(C)(C)O[Al+2].[H-].[H-].[H-].[Li+]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875871 0.95
SCHEMBL452898 0.91
Lithium Ion SCHEMBL11310421 0.64
Lithium Ion SCHEMBL11315029 0.64
Lithium Ion SCHEMBL3369260 0.64
Lithium Ion SCHEMBL589 0.58 TSHR (0.31)
Lithium Ion SCHEMBL8992466 0.58 TSHR (0.31)
Lithium Ion SCHEMBL11752150 0.58 TSHR (0.31)
Lithium Ion SCHEMBL10389521 0.57
Tert-Butyl Hydroperoxide SCHEMBL3026366 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2429982-A1 METHODS OF MAKING LUBIPROSTONE AND INTERMEDIATES THEREOF Apotex Pharmachem Inc. (CA) 2012-03-21 EP claimed
WO-2010083597-A1 METHODS OF MAKING LUBIPROSTONE AND INTERMEDIATES THEREOF APOTEX PHARMACHEM INC. (CA) 2010-07-29 WO claimed
EP-0289307-B1 OPTICALLY ACTIVE AROMATIC CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-08 EP claimed
EP-0289307-A2 Optically active aromatic carboxylic acid derivatives and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-02 EP claimed
US-20250214923-A1 DIESTER COMPOUND HAVING A DIMETHYLCYCLOBUTANE RING, A PROCESS FOR PREPARING THE SAME, AND A PROCESS FOR PREPARING DIMETHYLCYCLOBUTANE COMPOUND DERIVED FROM THE DIESTER COMPOUND SHINETSU CHEMICAL CO (JP) 2025-07-03 US disclosed
US-12281069-B2 Diester compound having a dimethylcyclobutane ring, a process for preparing the same, and a process for preparing dimethylcyclobutane compound derived from the diester compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-22 US disclosed
EP-3766861-B1 DIESTER COMPOUND HAVING A DIMETHYLCYCLOBUTANE RING, A PROCESS FOR PREPARING THE SAME, AND A PROCESS FOR PREPARING DIMETHYLCYCLOBUTANE COMPOUND DERIVED FROM THE DIESTER COMPOUND SHINETSU CHEMICAL CO (JP) 2023-05-24 EP disclosed
US-20220259136-A1 DIESTER COMPOUND HAVING A DIMETHYLCYCLOBUTANE RING, A PROCESS FOR PREPARING THE SAME, AND A PROCESS FOR PREPARING DIMETHYLCYCLOBUTANE COMPOUND DERIVED FROM THE DIESTER COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-08-18 US disclosed
US-11352312-B2 Diester compound having a dimethylcyclobutane ring, a process for preparing the same, and a process for preparing dimethylcyclobutane compound derived from the diester compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-06-07 US disclosed
US-20210017115-A1 DIESTER COMPOUND HAVING A DIMETHYLCYCLOBUTANE RING, A PROCESS FOR PREPARING THE SAME, AND A PROCESS FOR PREPARING DIMETHYLCYCLOBUTANE COMPOUND DERIVED FROM THE DIESTER COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-01-21 US disclosed
EP-3766861-A1 DIESTER COMPOUND HAVING A DIMETHYLCYCLOBUTANE RING, A PROCESS FOR PREPARING THE SAME, AND A PROCESS FOR PREPARING DIMETHYLCYCLOBUTANE COMPOUND DERIVED FROM THE DIESTER COMPOUND Shin-Etsu Chemical Co., Ltd. (JP) 2021-01-20 EP disclosed
US-20190070305-A1 BENZODIAZEPINES AND CONJUGATES THEREOF IMMUNOGEN, INC. 2019-03-07 US disclosed
EP-0284371-B1 NOVEL OPTICALLY ACTIVE BENZENE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND LIQUID-CRYSTALLINE SUBSTANCES CONTAINING SAID DERIVATIVES AS ACTIVE INGREDIENT AND OPTICAL SWITCHING ELEMENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-16 EP disclosed
US-5002693-A Novel optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-03-26 US disclosed
CN-87107990-A Novel benzothiadiazine, its preparation method and pharmaceutical composition thereof 1988-06-01 CN disclosed
US-4073899-A 7A-METHYL-ESTR-5-ENE-3B,17B-DIOL AND 17-ACYL ESTERS RICHARDSON-MERRELL, INC. (US) 1978-02-14 US disclosed
US-4038272-A STEREOSPECIFIC SYNTHESES OF 24R,25- AND 24S,25-DIHYDROXYCHOLESTEROL AND ALKANOYL DERIVATIVES THEREOF HOFFMANN-LA ROCHE INC. (US) 1977-07-26 US disclosed
US-4036978-A ANTIINFLAMMATORY AGENTS SANDOZ, INC. (US) 1977-07-19 US disclosed
US-3965120-A Prostaglandin E1 intermediate 3-carboxymethyl-4-methyl-2-1-carboxy-7-(loweralkoxy or aralkoxycarbonyl)-heptyl]-4-hydroxybutyric acid, γ-lactone, and processes of their preparation MERCK & CO., INC. (US) 1976-06-22 US disclosed
US-3939182-A Prostaglandin E1 intermediate 6α-carboxy-5α(1-hydroxyethyl)-2-cyclohexene-1-heptanoic acid,γ-lactone, and lower alkyl or aralkyl esters thereof MERCK & CO., INC. (US) 1976-02-17 US disclosed