Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL9293243 | 0.96 | — | — | |
| Lithium Ion SCHEMBL2059893 | 0.96 | — | — | |
| Lithium Ion SCHEMBL14812375 | 0.96 | — | — | |
| Lithium Ion SCHEMBL9293254 | 0.96 | — | — | |
| Lithium Ion SCHEMBL11332262 | 0.92 | TSHR (0.31) | TSHRTDP1ALDH1A1 | |
| SCHEMBL3898653 | 0.92 | TSHR (0.31) | TSHRTDP1ALDH1A1 | |
| Potassium Ion SCHEMBL3889958 | 0.92 | TSHR (0.31) | TSHRTDP1ALDH1A1 | |
| Lithium Ion SCHEMBL11332267 | 0.92 | TSHR (0.31) | TSHRTDP1ALDH1A1 | |
| Lithium Ion SCHEMBL808460 | 0.92 | TSHR (0.31) | TSHRTDP1ALDH1A1 | |
| SCHEMBL107947 | 0.92 | ALDH1A1 (0.36) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2805 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250327212-A1 | A METHOD FOR HIGH YIELD NANOWIRE SYNTHESIS | UNIV LIMERICK (IE) | 2025-10-23 | — | — | US | claimed |
| EP-4613745-A2 | PROCESS FOR PREPARING A COT INHIBITOR COMPOUND | Gilead Sciences, Inc. (US) | 2025-09-10 | — | — | EP | claimed |
| CN-120004965-A | Synthesis method of dydrogesterone advanced intermediate | 中国科学院上海有机化学研究所 | 2025-05-16 | — | — | CN | claimed |
| CN-119661551-A | Preparation method of (3R, 4S) -3-methyl-2-oxa-8-azaspiro [4.5] decan-4-amine hydrochloride | 重庆大学 | 2025-03-21 | — | — | CN | claimed |
| EP-4522334-A1 | A METHOD FOR HIGH YIELD NANOWIRE SYNTHESIS | University of Limerick (IE) | 2025-03-19 | — | — | EP | claimed |
| CN-119390681-A | Process for preparing COT inhibitor compounds | 吉利德科学公司 | 2025-02-07 | — | — | CN | claimed |
| CN-118530145-A | Synthesis method of darunavir key intermediate | 江苏八巨药业有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-118231759-A | In-situ polymerization solid electrolyte, method for preparing solid electrolyte by in-situ polymerization, solid battery, method for preparing solid battery and power utilization device | 深圳欣界能源科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| US-20240182940-A1 | Enhanced Sophorolipid Derivatives | LOCUS SOLUTIONS IPHOLDCO, LLC | 2024-06-06 | — | — | US | claimed |
| CN-118080011-A | Catalyst for preparing methanol by hydrogenation of carbon dioxide, preparation method and application thereof | 国家能源集团新能源技术研究院有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-1989001483-A1 | CONVERSION OF STEROIDAL 17-CYANOHYDRINS TO CORTICOIDS | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | claimed |
| EP-0189281-B1 | ANTIBACTERIAL DERIVATIVES OF A NEUTRAL MACROLIDE | PFIZER INC. (US) | 1988-08-10 | — | — | EP | claimed |
| EP-0114612-B1 | RACEMIC AND OPTICALLY ACTIF 3-HYDROXY-ALPHA-CYCLOCITRAL, THEIR ACETALS AND OPTICALLY ACTIF 3-OXO-ALPHA-CYCLOCITRALACETALS, AND ALSO THE PREPARATION AND USE OF THESE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1988-03-23 | — | — | EP | claimed |
| EP-0189281-A2 | Antibacterial derivatives of a neutral macrolide | PFIZER INC. (US) | 1986-07-30 | — | — | EP | claimed |
| EP-0041661-B1 | PREPARATION OF INTERMEDIATES OF CARBAPROSTACYCLINES | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-07-18 | — | — | EP | claimed |
| US-4359581-A | Process for the production of caracyclin intermediates | SCHERING AG (DE) | 1982-11-16 | — | — | US | claimed |
| US-4127651-A | ZOAPATLE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1978-11-28 | — | — | US | claimed |
| US-4112078-A | ACYLATION, REDUCTION, ZOAPATLE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1978-09-05 | — | — | US | claimed |
| US-4052407-A | ENZYME INHIBITORS, MULTISTAGE | GYOGYSZERKUTATO INTEZET (HU) | 1977-10-04 | — | — | US | claimed |
| US-3962218-A | NOVEL PROSTANOIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | claimed |