Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982611 | 0.83 | HSD17B10 (0.59) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL11511266 | 0.81 | HSD17B10 (0.53) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL16856424 | 0.79 | HSD17B10 (0.50) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL3853354 | 0.79 | BACE1 (0.51) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL10055034 | 0.77 | HDAC1 (0.54) | HSD17B10KDM4EHPGDTSHRSMN1; SMN2 | |
| SCHEMBL11935875 | 0.76 | HDAC1 (0.48) | BACE1HSD17B10KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL12074306 | 0.76 | HSD17B10 (0.47) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL17595673 | 0.76 | GPR68 (0.49) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL4571036 | 0.76 | HSD17B10 (0.71) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL30464743 | 0.76 | HSD17B10 (0.71) | BACE1HSD17B10KDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |