Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578804 | 0.84 | KMT2A (0.69) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL14284024 | 0.81 | SMN1; SMN2 (0.55) | ALDH1A1HTTSMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL9313982 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2ASMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL4534187 | 0.81 | SMN1; SMN2 (0.58) | ALDH1A1HTTSMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL3884253 | 0.81 | KDM4E (0.51) | ALDH1A1KMT2ASMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL9314030 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTKMT2ASMN1; SMN2CFTR | |
| SCHEMBL3048419 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2ASMN1; SMN2CFTRSLC6A2 | |
| SCHEMBL28421108 | 0.80 | CYP19A1 (0.58) | ALDH1A1KMT2ASMN1; SMN2KDM4EKCNA5 | |
| SCHEMBL30430689 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2ASMN1; SMN2CFTR | |
| SCHEMBL28205036 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2CFTRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139850-B1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC (CA) | 2018-09-12 | — | — | EP | disclosed |
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | ALDH1A1 532/4885HTT 1010/4885KMT2A 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.