Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2949499 | 1.00 | LPL (0.45) | LPLLIPGESR1TLR8MEN1 | |
| SCHEMBL2956576 | 1.00 | LPL (0.45) | LPLLIPGESR1TLR8MEN1 | |
| SCHEMBL14282522 | 0.86 | LPL (0.38) | LPLLIPGESR1TLR8 | |
| SCHEMBL2867772 | 0.86 | LPL (0.52) | LPLLIPGESR1TLR8 | |
| SCHEMBL15509385 | 0.86 | LPL (0.43) | LPLLIPGTSHRNR5A1TP53 | |
| SCHEMBL13429494 | 0.84 | LPL (0.42) | LPLLIPGESR1MEN1KMT2A | |
| SCHEMBL22748290 | 0.83 | LPL (0.40) | LPLLIPGESR1TLR8CHUK | |
| SCHEMBL20819729 | 0.81 | LPL (0.38) | LPLLIPGESR1TLR8MEN1 | |
| SCHEMBL22748469 | 0.81 | LPL (0.43) | LPLLIPGESR1MEN1KMT2A | |
| SCHEMBL4262878 | 0.80 | CYP19A1 (0.34) | TLR8MEN1KMT2ANR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217136-B2 | Process for preparing thieno[3,4-B] pyrazine copolymers,thieno[3,4-B]—pyrazine copolymers prepared by this process, and their use | Thüringisches Institut für Textil-und Kunststoff-Forschung E.V. (DE) | 2012-07-10 | — | — | US | disclosed |
| US-20090227763-A1 | Process for Preparing Thieno[3,4-B] Pyrazine Copolymers,Thieno[3,4-B]- Pyrazine Copolymers Prepared by this Process, and their use | THURINGISCHES INSTITUT FUR TEXTIL-UND KUNSTSTOFF-FORSCHUNG E.V. (DE) | 2009-09-10 | — | — | US | disclosed |
| EP-1999760-A1 | PROCESS FOR PREPARING THIENOÝ3,4-B¨PYRAZINE COPOLYMERS, THIENOÝ3,4-B¨-PYRAZINE COPOLYMERS PREPARED BY THIS PROCESS, AND THEIR USE | THÜRINGISCHES INSTITUT FÜR TEXTIL- UND KUNSTSTOFF-FORSCHUNG E.V. (DE) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007110062-A1 | PROCESS FOR PREPARING THIENO[3,4-B]PYRAZINE COPOLYMERS, THIENO[3,4-B]-PYRAZINE COPOLYMERS PREPARED BY THIS PROCESS, AND THEIR USE | Thüringisches Institut für Textil- und Kunststoff-Forschung e.V. (DE) | 2007-10-04 | — | — | WO | disclosed |