Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21655144 | 0.99 | LPL (0.42) | LPLLIPGS1PR5S1PR1ESR1 | |
| SCHEMBL30129568 | 0.83 | LPL (0.34) | LPLLIPGHTR2BKMT2A | |
| SCHEMBL23692656 | 0.81 | LPL (0.37) | LPLLIPG | |
| SCHEMBL4530065 | 0.81 | LPL (0.45) | LPLLIPGESR1MEN1NR1I2 | |
| SCHEMBL2956576 | 0.81 | LPL (0.45) | LPLLIPGESR1MEN1NR1I2 | |
| SCHEMBL2949499 | 0.81 | LPL (0.45) | LPLLIPGESR1MEN1NR1I2 | |
| SCHEMBL2867772 | 0.80 | LPL (0.52) | LPLLIPGESR1 | |
| SCHEMBL15509385 | 0.80 | LPL (0.43) | LPLLIPGTHRATHRB | |
| SCHEMBL22748290 | 0.80 | LPL (0.40) | LPLLIPGS1PR5S1PR1ESR1 | |
| SCHEMBL7789302 | 0.80 | S1PR5 (0.38) | S1PR5S1PR1THRATHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245297-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |