⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214294 | 0.80 | MAPT (0.42) | — | |
| SCHEMBL270567 | 0.77 | — | — | |
| SCHEMBL12475358 | 0.74 | — | — | |
| SCHEMBL364354 | 0.72 | — | — | |
| SCHEMBL10493698 | 0.72 | — | — | |
| SCHEMBL8012278 | 0.72 | CA1 (0.36) | — | |
| SCHEMBL8996417 | 0.72 | LMNA (0.40) | — | |
| SCHEMBL271616 | 0.71 | — | — | |
| SCHEMBL8130582 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL6602279 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410881-B1 | Semisynthetic ganglioside analogues | FIDIA SPA (IT) | 1997-09-17 | — | — | EP | claimed |
| EP-0410881-A2 | Semisynthetic ganglioside analogues | FIDIA S.p.A. (IT) | 1991-01-30 | — | — | EP | claimed |
| EP-2457593-A1 | Cyclic RGD peptides of amino acids based on thiazoles or oxazoles as selective antagonists of the alpha-v beta-3 integrin | Lykera Biomed S.A. (ES) | 2012-05-30 | — | — | EP | disclosed |
| WO-2012062777-A1 | CYCLIC RGD PEPTIDES OF AMINO ACIDS BASED ON THIAZOLES OR OXAZOLES AS SELECTIVE ANTAGONISTS OF THE ALFA ανβ3 INTEGRIN | LYKERA BIOMED SA (ES) | 2012-05-18 | — | — | WO | disclosed |
| CN-101065351-A | Carboxamides and their use | GIVAUDAN SA (CH) | 2007-10-31 | — | — | CN | disclosed |
| EP-0410881-B1 | Semisynthetic ganglioside analogues | FIDIA SPA (IT) | 1997-09-17 | — | — | EP | disclosed |
| US-5484775-A | FOR INHIBITING GLUTAMATE-INDUCED NEUROTOXICITY | FIDIA S.P.A. (IT) | 1996-01-16 | — | — | US | disclosed |
| EP-0410881-A2 | Semisynthetic ganglioside analogues | FIDIA S.p.A. (IT) | 1991-01-30 | — | — | EP | disclosed |
| US-4804742-A | OSTEOPOROSIS TREATMENT OF EXTENDED DURATION | RORER PHARMACEUTICAL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0249096-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1987-12-16 | — | — | EP | disclosed |
| US-4650854-A | OSTEOPOROSIS | USV PHARMACEUTICAL CORPORATION (US) | 1987-03-17 | — | — | US | disclosed |