Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2007840 | 1.00 | — | — | |
| Acetic Acid SCHEMBL2140076 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL5819601 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL28674854 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL503041 | 0.97 | — | — | |
| Acetic Acid SCHEMBL11054868 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL6838880 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL1321891 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL727012 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL10983317 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090033223-A1 | CONDUCTIVE FILM, ELECTRON EMITTING DEVICE AND IMAGE DISPLAY APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2009-02-05 | — | — | US | disclosed |