Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3650850 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL503041 | 0.97 | — | — | |
| Acetic Acid SCHEMBL2140076 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL28674854 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL11054868 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL5819601 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL10983317 | 0.93 | — | — | |
| Acetic Acid SCHEMBL4530471 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL699745 | 0.93 | — | — | |
| Acetic Acid SCHEMBL6838880 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028508-B | Ethylene tetramerization process with reduced PE (polyethylene) production | 万华化学集团股份有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-111132700-B | Dual-mode radiotracer and therapeutic agent | 慕尼黑工业大学 | 2022-12-13 | — | — | CN | claimed |
| CN-114686115-A | Chemical mechanical polishing solution and use method thereof | 安集微电子科技（上海）股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| EP-1692145-B1 | METHODS FOR PRODUCING COPPER ETHANOLAMINE SOLUTIONS | ARCH CHEM INC (US) | 2013-09-04 | — | — | EP | claimed |
| EP-2474328-A2 | Mechanism-based targeted pancreatic beta cell imaging and therapy | Board Of Regents, The University Of Texas System (US) | 2012-07-11 | — | — | EP | claimed |
| US-20100278731-A1 | Mechanism-Based Targeted Pancreatic Beta Cell Imaging and Therapy | YANG DAVID J | 2010-11-04 | — | — | US | claimed |
| CN-1867363-B | Composition for imaging pancreas and use thereof | UNIV TEXAS | 2010-05-12 | — | — | CN | claimed |
| EP-1675625-A4 | MECHANISM-BASED TARGETED PANCREATIC BETA CELL IMAGING AND THERAPY | UNIV TEXAS (US) | 2009-07-15 | — | — | EP | claimed |
| CN-101321542-A | Microparticles for microarterial imaging and radiotherapy | UNIV MARYLAND (US) | 2008-12-10 | — | — | CN | claimed |
| CN-1867363-A | Mechanism-based targeted pancreatic beta cell imaging and therapy | UNIV TEXAS (US) | 2006-11-22 | — | — | CN | claimed |
| EP-0752873-A4 | LABELLED PEPTIDE COMPOUNDS | MALLINCKRODT INC (US) | 2002-05-15 | — | — | EP | claimed |
| US-6312661-B1 | DETECTION OF TUMORS, RADIOACTIVE ISOTOPES, AGONIST OR ANTAGONIST, METALS AND HALOGENS | MALLINCKRODT INC. | 2001-11-06 | — | — | US | claimed |
| US-6194386-B1 | SELECTIVE AFFINITY TO NEUROTENSIN RECEPTORS, COMPARABLE WITH THAT OF NEUROTENSIN ITSELF, AND WHICH HAS SUFFICIENT ENZYMATIC RESISTANCE TO ALLOW ITS USE IN DIAGNOSIS AND THERAPY; RADIOACTIVE CHELATE PEPTIDES; IN VIVO STABILITY | MALLINCKRODT INC. | 2001-02-27 | — | — | US | claimed |
| US-5952464-A | OLIGOPEPTIDE WITH SELECTIVE NEUROTENSIN RECEPTOR AFFINITY LABELLED WITH METAL ISOTOPE OR RADIOACTIVE HALOGEN ISOTOPE; FOR DIAGNOSTIC IMAGING AND ANTICARCINOGENIC AGENTS | MALLINCKRODT INC. (US) | 1999-09-14 | — | — | US | claimed |
| EP-0885017-A2 | USE OF LABELLED CCK-B RECEPTOR LIGANDS FOR THE DETECTION AND LOCALIZATION OF MALIGNANT HUMAN TUMOURS | MALLINCKRODT MEDICAL, INC. (US) | 1998-12-23 | — | — | EP | claimed |
| WO-1997031657-A2 | USE OF LABELLED CCK-B RECEPTOR LIGANDS FOR THE DETECTION AND LOCALIZATION OF MALIGNANT HUMAN TUMORS | MALLINCKRODT MEDICAL, INC. (US) | 1997-09-04 | — | — | WO | claimed |
| EP-0752873-A1 | LABELLED PEPTIDE COMPOUNDS | MALLINCKRODT MEDICAL, INC. (US) | 1997-01-15 | — | — | EP | claimed |
| WO-1996023527-A1 | METHOD FOR THE DETECTION AND LOCALIZATION OF MALIGNANT HUMAN TUMOURS | MALLINCKRODT MEDICAL, INC. (US) | 1996-08-08 | — | — | WO | claimed |
| WO-1995022341-A1 | LABELLED PEPTIDE COMPOUNDS | MALLINCKRODT MEDICAL, INC. (US) | 1995-08-24 | — | — | WO | claimed |
| US-5128046-A | Chelation, coagulation, water pollution control | NALCO CHEMICAL COMPANY (US) | 1992-07-07 | — | — | US | claimed |