Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.77 |
| ▸ | PPARG | P37231 | 2/20 | 0.77 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.72 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | MMP12 | P39900 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699371 | 0.95 | PPARD (0.74) | PPARDPPARGFFAR1GSTP1ALOX15 | |
| SCHEMBL1115002 | 0.90 | PPARG (0.71) | PPARDPPARGFFAR1ALOX15FFAR4 | |
| SCHEMBL422442 | 0.89 | ALOX15 (0.76) | PPARDPPARGFFAR1ALOX15PPARA | |
| SCHEMBL5205577 | 0.87 | FFAR1 (0.72) | PPARDPPARGFFAR1GSTP1FFAR4 | |
| SCHEMBL1756380 | 0.87 | FFAR1 (0.72) | PPARDPPARGFFAR1GSTP1FFAR4 | |
| Bicarbonate SCHEMBL9638235 | 0.86 | FFAR1 (0.71) | PPARDPPARGFFAR1GSTP1FFAR4 | |
| SCHEMBL1746856 | 0.86 | PPARD (0.81) | PPARDPPARGFFAR1FFAR4PPARA | |
| SCHEMBL13918253 | 0.84 | FFAR1 (0.61) | PPARDPPARGFFAR1GSTP1ADAMTS5 | |
| SCHEMBL1746845 | 0.84 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1PTGER4 | |
| SCHEMBL2780802 | 0.84 | ALOX15 (0.71) | PPARDPPARGFFAR1ALOX15PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20060154912-A1 | Isophtalic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154912-A1 | Isophtalic acid derivatives | VHL, FABP3, CPT1A | PPARD 59/4885PPARG 194/4885FFAR1 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.