Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.62 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.59 |
| ▸ | PPARD | Q03181 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | MMP12 | P39900 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756380 | 1.00 | FFAR1 (0.72) | FFAR1ABCC4LMNAGAATSHR | |
| SCHEMBL1066614 | 0.91 | FFAR1 (0.70) | FFAR1LMNAPTGS1FFAR4ALOX5 | |
| Ammonia Solution, Strong SCHEMBL27788257 | 0.90 | FFAR1 (0.68) | FFAR1LMNAPTGS1FFAR4ALOX5 | |
| SCHEMBL4222632 | 0.90 | FFAR1 (0.68) | FFAR1LMNAPTGS1FFAR4ALOX5 | |
| Hydrochloric Acid SCHEMBL10622121 | 0.90 | FFAR1 (0.68) | FFAR1LMNAPTGS1FFAR4ALOX5 | |
| SCHEMBL6182 | 0.90 | FFAR1 (0.69) | FFAR1ABCC4LMNAGAATSHR | |
| SCHEMBL1756354 | 0.87 | MAOB (0.60) | FFAR1ABCC4LMNAGAATSHR | |
| SCHEMBL6341082 | 0.87 | FFAR1 (0.68) | FFAR1LMNAPTGS1FFAR4PPARD | |
| SCHEMBL4530835 | 0.87 | PPARD (0.77) | FFAR1GSTP1FFAR4PPARDPPARG | |
| Bicarbonate SCHEMBL9638235 | 0.86 | FFAR1 (0.71) | FFAR1LMNAPTGS1GSTP1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | disclosed |
| US-20050228020-A1 | Beta secretase inhibitors | MIYAMOTO MASAOMI | 2005-10-13 | — | — | US | disclosed |
| EP-1572628-A1 | ISOPHTALIC ACID DERIVATIVES | Bayer HealthCare AG (DE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004052839-A1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-06-24 | — | — | WO | disclosed |
| US-20040110743-A1 | -Secretase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-10 | — | — | US | disclosed |
| US-6586475-B1 | 5-chloro-N-(2-N,N-diethylamino)ethyl)-2- methoxy-4-(1-naphthoylamino)benzamide and prodrugs, used for prevention of neurodegenarative diseases such as Alzheimer's disease | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1283039-A1 | -SECRETASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
| EP-1132376-A1 | BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228020-A1 | Beta secretase inhibitors | BACE1, BACE2, APP | FFAR1 1517/4885ABCC4 1866/4885LMNA 2863/4885 |
| US-20040110743-A1 | -Secretase inhibitors | BACE1, BACE2, PSEN1 | FFAR1 1621/4885ABCC4 3317/4885LMNA 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.