Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453120 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2CA14CA12KMT2ALMNA | |
| SCHEMBL8355254 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14CA12KMT2A | |
| SCHEMBL1332029 | 0.77 | — | — | |
| SCHEMBL270012 | 0.77 | — | — | |
| SCHEMBL6527167 | 0.76 | — | — | |
| SCHEMBL4110912 | 0.76 | — | — | |
| SCHEMBL269783 | 0.76 | — | — | |
| SCHEMBL7944709 | 0.74 | — | — | |
| SCHEMBL29271671 | 0.73 | LMNA (0.36) | CA14CA12KMT2ALMNA | |
| SCHEMBL7583623 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2CA14CA12KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106467492-B | preparation method of polyfluoromethyl pyrazole compound, intermediate and preparation method | 联化科技(盐城)有限公司 | 2019-12-17 | — | — | CN | disclosed |