Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.54 |
| ▸ | IL1B | P01584 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536523 | 0.92 | P2RX7 (0.63) | P2RX7IL1BSLC6A9 | |
| SCHEMBL3642508 | 0.87 | P2RX7 (0.65) | P2RX7IL1B | |
| SCHEMBL3691548 | 0.81 | P2RX7 (0.54) | P2RX7IL1BSLC6A9 | |
| SCHEMBL3646428 | 0.81 | P2RX7 (0.64) | P2RX7IL1BSLC6A9 | |
| SCHEMBL3645343 | 0.81 | P2RX7 (0.54) | P2RX7IL1BSLC6A9 | |
| SCHEMBL13706719 | 0.81 | P2RX7 (0.55) | P2RX7IL1BSLC6A9 | |
| SCHEMBL4531028 | 0.80 | P2RX7 (0.60) | P2RX7IL1BSLC6A9 | |
| SCHEMBL4532197 | 0.79 | P2RX7 (0.51) | P2RX7IL1BSLC6A9 | |
| SCHEMBL3638935 | 0.79 | P2RX7 (0.51) | P2RX7IL1BSLC6A9 | |
| SCHEMBL11885591 | 0.79 | P2RX7 (0.61) | P2RX7IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | claimed |
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |