Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.60 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688124 | 0.90 | P2RX7 (0.58) | P2RX7SLC6A9IL1BLMNA | |
| SCHEMBL4536523 | 0.88 | P2RX7 (0.63) | P2RX7SLC6A9IL1BMEN1ALDH1A1 | |
| SCHEMBL13706752 | 0.84 | P2RX7 (0.47) | P2RX7IL1B | |
| SCHEMBL4528078 | 0.84 | P2RX7 (0.47) | P2RX7IL1B | |
| SCHEMBL3646428 | 0.81 | P2RX7 (0.64) | P2RX7SLC6A9IL1B | |
| SCHEMBL3645343 | 0.81 | P2RX7 (0.54) | P2RX7SLC6A9IL1BLMNA | |
| SCHEMBL3691548 | 0.81 | P2RX7 (0.54) | P2RX7SLC6A9IL1BMEN1ALDH1A1 | |
| SCHEMBL3647578 | 0.80 | P2RX7 (0.59) | P2RX7SLC6A9IL1BMEN1ALDH1A1 | |
| SCHEMBL13706719 | 0.80 | P2RX7 (0.55) | P2RX7SLC6A9IL1BMEN1ALDH1A1 | |
| SCHEMBL4531759 | 0.80 | P2RX7 (0.54) | P2RX7SLC6A9IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | claimed |