SCHEMBL943732

SCHEMBL943732

O=S(=O)(O)c1ccc2ccccc2c1N=Nc1c(O)ccc2ccccc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 7/20 0.76
CTRC Q99895 2/20 0.76
MAPT P10636 7/20 0.63
KMT2A Q03164 4/20 0.63
TDP1 Q9NUW8 4/20 0.63
MAPK1 P28482 4/20 0.63
GAA P10253 2/20 0.63
CYP1A2 P05177 1/20 0.62
CYP2C9 P11712 1/20 0.62
TSHR P16473 1/20 0.62
PTPRA P18433 1/20 0.62
PTPRB P23467 1/20 0.62
CYP2C19 P33261 1/20 0.62
HIF1A Q16665 1/20 0.62
RAPGEF4 Q8WZA2 1/20 0.62
HSD17B10 Q99714 1/20 0.62
MEN1 O00255 3/20 0.59
THRB P10828 3/20 0.59
CTRB1 P17538 1/20 0.57
L3MBTL1 Q9Y468 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30049470 0.87 CTRB1 (0.73) MPLCTRCMAPTKMT2ATDP1
SCHEMBL6763835 0.87 CTRB1 (0.73) MPLCTRCMAPTKMT2ATDP1
SCHEMBL5701120 0.87 CTRB1 (0.73) MPLCTRCMAPTKMT2ATDP1
SCHEMBL4532468 0.87 MPL (0.71) MPLCTRCMAPTKMT2ATDP1
SCHEMBL29362358 0.87 MPL (1.00) MPLCTRCMAPTKMT2ATDP1
SCHEMBL3010602 0.87 MPL (1.00) MPLCTRCMAPTKMT2ATDP1
SCHEMBL30371538 0.87 MPL (1.00) MPLCTRCMAPTKMT2ATDP1
SCHEMBL7247118 0.87 MPL (1.00) MPLCTRCMAPTKMT2ATDP1
SCHEMBL31183028 0.87 MPL (0.71) MPLCTRCMAPTKMT2ATDP1
SCHEMBL4532471 0.87 MPL (0.71) MPLCTRCMAPTKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11110121-B2 Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances CLARIANT INTERNATIONAL LTD. (CH) 2021-09-07 US disclosed
US-10406135-B2 Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group CLARIANT INTERNATIONAL LTD. (CH) 2019-09-10 US disclosed
US-9834635-B2 Polymers based on arcrylic, methacrylic or ethacrylic amidoalkyl sulfonic acid or salts and carboxyalky acrylate, methacrylate or ethacrylate or oligomers of said carboxy compounds CLARIANT INTERNATIONAL LTD. (CH) 2017-12-05 US disclosed
US-20170105910-A1 UV FILTER CAPSULE BASF SE (DE) 2017-04-20 US disclosed
US-9622959-B2 Cross-linked polymere CLARIANT INTERNATIONAL LTD. (CH) 2017-04-18 US disclosed
US-9592185-B2 Compositions containing hydrogen peroxide or substances releasing hydrogen peroxide CLARIANT INTERNATIONAL LTD. (CH) 2017-03-14 US disclosed
US-9526687-B2 Polymers based on sulfonic acids, amides and special cross-linking agents CLARIANT INTERNATIONAL LTD. (CH) 2016-12-27 US disclosed
US-9295626-B2 Compositions comprising isosorbide monoester and N-hydroxypyridones CLARIANT INTERNATIONAL LTD. (CH) 2016-03-29 US disclosed
US-20160000080-A1 COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALIPHATIC VICINAL DIOLS CLARIANT INTERNATIONAL LTD. (CH) 2016-01-07 US disclosed
US-20150342856-A1 Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations CLARIANT FINANCE (BVI) LIMITED (VG) 2015-12-03 US disclosed
US-20060045856-A1 Composition containing a dihydroxyacetone precursor MERCK PATENT GMBH (DE) 2006-03-02 US disclosed
US-20050276763-A1 Emulsion concentrate containing water-soluble and oil-soluble polymers BEIERSDORF AG 2005-12-15 US disclosed
US-20050244443-A1 Cosmetic concentrate BEIERSDORF AG (DE) 2005-11-03 US disclosed
US-20050214333-A1 Cosmetic with sensitive ingredients BEIERSDORF AG 2005-09-29 US disclosed
US-20050201969-A1 Stable cosmetics BEIERSDORF AG 2005-09-15 US disclosed
US-20050074471-A1 Self-foaming or foamy preparations comprising particulate hydrophobic and/or hydrophobized and/or oil-absorbent solid substances BEIERSDORF AG (DE) 2005-04-07 US disclosed
US-20050025729-A1 Lipstick BEIERSDORF AG 2005-02-03 US disclosed
WO-2004092283-A2 ANTIMICROBIAL PIGMENTS MERCK PATENT GMBH (DE) 2004-10-28 WO disclosed
WO-2004091567-A2 COSMETIC FORMULATIONS COMPRISING ANTIMICROBIAL PIGMENTS MERCK PATENT GMBH (DE) 2004-10-28 WO disclosed
US-6620420-B2 Cosmetic or dermatological application BEIERSDORF AG (DE) 2003-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050244443-A1 Cosmetic concentrate MAN1B1, MAN2A1, MITF MPL 916/4885CTRC 3744/4885MAPT 987/4885
US-20050074471-A1 Self-foaming or foamy preparations comprising particulate hydrophobic and/or hydrophobized and/or oil-absorbent solid substances HBB, HBG1, FFAR1 MPL 3786/4885CTRC 3356/4885MAPT 2773/4885
US-20050276763-A1 Emulsion concentrate containing water-soluble and oil-soluble polymers PCNA, CUTA, PCLAF MPL 1664/4885CTRC 3199/4885MAPT 1772/4885
US-11110121-B2 Compositions comprising hydrogen peroxide or hydrogen peroxide donor substances GPX4, LPO, CAT MPL 2837/4885CTRC 872/4885MAPT 1729/4885
US-20170105910-A1 UV FILTER CAPSULE UROD, MITF, NISCH MPL 2774/4885CTRC 1453/4885MAPT 740/4885
US-20160000080-A1 COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALIPHATIC VICINAL DIOLS HSD17B12, DHCR7, ERG28 MPL 3866/4885CTRC 1900/4885MAPT 4194/4885
US-20150342856-A1 Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations C9, PARN, SGMS1 MPL 3930/4885CTRC 1458/4885MAPT 3015/4885
US-20060045856-A1 Composition containing a dihydroxyacetone precursor TYR, CUTA, DERA MPL 2680/4885CTRC 3276/4885MAPT 340/4885
US-10406135-B2 Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group ADH5, ADH1A, ADH1C MPL 4266/4885CTRC 785/4885MAPT 1822/4885
US-20050214333-A1 Cosmetic with sensitive ingredients CUTA, MITF, NISCH MPL 3980/4885CTRC 1863/4885MAPT 1425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.